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Using the fluorescent dye, double retrograde-labeling tracing technique, separate populations of insular cortex neurons were demonstrated to project to the amygdaloid central nucleus and to autonomic nuclei of the dorsal medulla. Both populations were located in layer V of the agranular and granular insula with neurons projecting to the dorsal medulla(More)
Evidence has recently been presented which demonstrates that the amygdaloid central nucleus projects directly upon cardiovascular/autonomic regulatory nuclei of the dorsal medulla and that in the rabbit this nucleus may influence cardiovascular activity during emotional states. The present study is one of a series of investigations designed to provide(More)
beta-Adrenergic antagonists injected into the amygdala complex of rats trained in a passive avoidance task produced time-dependent and dose-dependent decreases in retention of the task. In addition, the effects observed with beta-adrenergic antagonists were both stereospecific and reversed by norepinephrine. The results support a role for an amygdala(More)
OBJECTIVE To audit the outcome from pre-hospital cardiac arrest managed by ambulance personnel, and to assess their proficiency by analysing the time to initiate basic and advanced cardiac life support, the compliance with national guidelines, and the overall success of resuscitation. DESIGN A retrospective analysis of ambulance service report forms of(More)
This study assessed the ability of junior doctors in accident and emergency to detect radiographic abnormalities. Their assessments of 505 radiographs taken at nights and weekends over a period of 8 months and showing abnormalities were examined. Each assessment by a senior house officer (SHO) was compared with the subsequent diagnosis of a radiologist of(More)
There were significant differences in the time taken to resuscitate 257 trauma patients from four internationally recognized trauma centres. The fastest unit completed resuscitation in 15 min while the slowest took 105 min. This variation was not explained by differences in the type of patient dealt with, seniority of the team leader, or the number of(More)
AIM The Advanced Trauma Life Support system classifies the severity of shock. The aim of this study is to test the validity of this classification. METHODS Admission physiology, injury and outcome variables from adult injured patients presenting to hospitals in England and Wales between 1989 and 2007 and stored on the Trauma Audit and Research Network(More)
From a family tragedy 20 years ago, ATLS has truly become an international trauma care program. Its success is demonstrated not only in the large number of physicians that have been trained, but also in the appearance of a number of affiliated courses with a similar structure, aimed at training medical, nursing, civilian and military personnel in how to(More)
OBJECTIVES To study the current practice of rapid sequence intubations (RSIs) in four different emergency medicine training programmes in the UK. METHODS Observational study design involving four regional training programmes (Wessex, North West, Yorkshire, Avon). Data were collected in real time using a previously piloted survey tool. Data were collected(More)