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It has been estimated that a history of systemic embolism is likely to be obtained in 9 to 14% of patients suffering from rheumatic heart disease, and that the embolism is cerebral in about 60%, peripheral in 30%, and visceral in 10% of the cases (Wood, 1954, 1956). As arterial embolism can be a serious complication of rheumatic heart disease and can occur(More)
In a multicentre double-blind randomised study, the effect of sotalol 320 mg once daily was compared with that of placebo in patients surviving an acute myocardial infarction. Treatment was started 5--14 days after infarction in 1456 patients (60% being randomised to sotalol, and 40% to placebo) who represented 45% of those evaluated for entry. Patients(More)
The long-term results of 356 episodes of atrial defibrillation by DC shock carried out in 250 patients are reviewed. In 78 per cent of the cases, atrial fibrillation recurred by the end of 12 months in spite of the administration of quinidine or procainamide or propranolol, singly or combined. However, when no antidysrhythmic drugs were used the recurrence(More)
There are conflicting views regarding the incidence of paroxysmal tachycardia in pregnancy. Jensen (1938) concluded from a review of the literature that there had been only 19 cases reported up to 1938-in which the diagnosis was beyond reasonable doubt, and he thought that the condition was rare during pregnancy. On the other hand, Campbell (1947) was of(More)
The clinical aspects of rheumatic heart disease in relation to pregnancy are reviewed in a combined series of patients chiefly from the Newcastle General Hospital studied over a period of 28 years, and from the Western General Hospital in Edinburgh studied over 25 years. In both centres, since about I960, there has been a progressive decrease in the number(More)