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Glutathione peroxidase (GSHPx) is a critical intracellular enzyme involved in detoxification of hydrogen peroxide (H(2)O(2)) to water. In the present study we examined the susceptibility of mice with(More)
There is evidence that both inflammatory mechanisms and mitochondrial dysfunction contribute to Parkinson’s disease (PD) pathogenesis. We investigated whether the cyclooxygenase 2 (COX-2) inhibitor(More)
Impaired function of certain mitochondrial respiratory complexes has long been linked to the pathogenesis of chronic neurodegenerative disorders such as Parkinson's and Huntington's diseases.(More)