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BACKGROUND Selected groups of patients with bipolar and unipolar disorder have an increased mortality rate from suicide and natural causes of death. However, there has been no population-based study of mortality of patients followed up from the onset of the illness. METHODS All patients with a hospital diagnosis of bipolar (n = 15 386) or unipolar (n = 39(More)
A study of mortality for all patients with a first hospital diagnosis of schizophrenia in Stockholm County, Sweden, during 1973 to 1995 was performed, by linking the in-patient register with the national cause-of-death register. Overall and cause-specific standardized mortality ratios (SMR) were calculated by 5-year age classes and 5-year calendar time(More)
Studies on the suicide risk among patients with amyotrophic lateral sclerosis (ALS) in countries without legalized euthanasia or assisted suicide are important additions to data on the wish to die of these patients. We conducted a population-based cohort study in Sweden between 1965 and 2004, which comprised of 6,642 patients with incident ALS identified(More)
Previous reports regarding risk factors for suicide in schizophrenia have been inconclusive. We performed a matched case-control study of in-patient-treated schizophrenia patients in order to assess the suicide risk associated with socioeconomic, demographic, and psychiatric factors. The cases were 84 patients who died by suicide within five years after(More)
OBJECTIVES To investigate the temporal trend of amyotrophic lateral sclerosis (ALS) incidence in Sweden between January 1, 1991, and December 31, 2005, and to explore incidence variations according to major demographic factors. DESIGN Population-based study. SETTING Academic research. PARTICIPANTS All incident cases of ALS identified through the(More)
OBJECTIVE To assess the relative risk for amyotrophic lateral sclerosis (ALS) in families of ALS patients. METHODS We conducted a cohort study based on the Swedish Multi-Generation Register in 1961 to 2005. Among 6,671 probands (first ALS case in the family), 1,909 full siblings, 13,947 children, and 5,405 spouses were identified (exposed group). Other(More)
The aim of this study was to estimate suicide risk during hospitalization and in the year following discharge for patients with mental disorders. All suicide cases in Sweden 18 years and older, between 1991 and 2003 (N=20,675; 70% male), were individually matched to 10 controls from the general Swedish population. Discharge diagnoses in the year before(More)
OBJECTIVE To determine whether detection of invasive cervical cancer by screening results in better prognosis or merely increases the lead time until death. DESIGN Nationwide population based cohort study. SETTING Sweden. PARTICIPANTS All 1230 women with cervical cancer diagnosed during 1999-2001 in Sweden prospectively followed up for an average of(More)
BACKGROUND Incidence of condyloma, or genital warts (GW), is the earliest possible disease outcome to measure when assessing the effectiveness of human papillomavirus (HPV) vaccination strategies. Efficacy trials that follow prespecified inclusion and exclusion criteria may not be fully generalizable to real-life HPV vaccination programs, which target a(More)
OBJECTIVE To assess the risk of serious adverse events after vaccination of adolescent girls with quadrivalent human papillomavirus (qHPV) vaccine. DESIGN Register based cohort study. SETTING Denmark and Sweden, October 2006 to December 2010. PARTICIPANTS 997,585 girls aged 10-17, among whom 296,826 received a total of 696,420 qHPV vaccine doses. (More)