Ozgur Oksuz

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Glioblastoma (GBM) is thought to be driven by a subpopulation of cancer stem cells (CSCs) that self-renew and recapitulate tumor heterogeneity yet remain poorly understood. Here, we present a comparative analysis of chromatin state in GBM CSCs that reveals widespread activation of genes normally held in check by Polycomb repressors. These activated targets(More)
Erk1/2 activation contributes to mouse ES cell pluripotency. We found a direct role of Erk1/2 in modulating chromatin features required for regulated developmental gene expression. Erk2 binds to specific DNA sequence motifs typically accessed by Jarid2 and PRC2. Negating Erk1/2 activation leads to increased nucleosome occupancy and decreased occupancy of(More)
Many smartphone applications are web based and rely on cookies to maintain the status of a web session. Cookies, however, may lead to security threats since they may contain sensitive information. In addition, an attacker having access to a cookie can easily impersonate the legitimate user. In this paper, we propose and implement a system that securely(More)
Wireless network traces have been widely used to understand human behaviors and provide value-added services. Sanitization based techniques have been shown to be severely lacking in protecting sensitive user information embedded in such traces. In this paper, we take an encryption based approach that provides much stronger protection of user privacy. One(More)
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