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TALE factors use two distinct functional modes to control an essential zebrafish gene expression program
TALE factors are broadly expressed embryonically and known to function in complexes with transcription factors (TFs) like Hox proteins at gastrula/segmentation stages, but it is unclear if suchExpand
Ciliary signaling cascades in photoreceptors
For being a polarized neuron and having a sensory cilium, photoreceptors attract remarkable attention. This is due their highly polarized structure and active visual signal transduction cascades andExpand
Zebrafish prdm12b acts independently of nkx6.1 repression to promote eng1b expression in the neural tube p1 domain
BackgroundFunctioning of the adult nervous system depends on the establishment of neural circuits during embryogenesis. In vertebrates, neurons that make up motor circuits form in distinct domainsExpand
Zebrafish prdm 12 b acts independently of nkx 6 . 1 repression to promote eng 1 b expression in the neural tube p 1 domain
Background: Functioning of the adult nervous system depends on the establishment of neural circuits during embryogenesis. In vertebrates, neurons that make up motor circuits form in distinct domainsExpand
Tackling Primary Cilia Dysfunction in Photoreceptor Degenerative Diseases of the Eye.
Perception of what is occurring around us relies extensively on our senses, such as vision, smell and touch. Among these, vision attracts remarkable attention. The ability to see makes us appreciateExpand
Understanding the Role of Prdm12b in Zebrafish Development
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Photoreceptor Sensory Cilium and Associated Disorders
The primary cilium is a microtubule-based extension of the plasma membrane, which is present in almost all cell types. Ciliary microtubules extend from a basal body (or mother centriole), which docksExpand