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OBJECTIVE Cell therapy is an exciting area of investigation for repair of injured myocardial tissue. Platelet-rich plasma (PRP) is an autologous fractionation of whole blood containing high concentrations of growth factors including vascular endothelial growth factor and insulin-like growth factor, among many others. PRP has been shown to safely and(More)
OBJECTIVES Respiratory syncytial virus (RSV) is an important cause of upper respiratory infections and is known to play a causal role in the pathogenesis of rhinitis, sinusitis, acute otitis media, and pneumonia. RSV appears to prime the respiratory tract to secondary inciting events, such as bacterial or antigen challenges. To study the proinflammatory(More)
IMPORTANCE Thoracic endovascular aortic repair (TEVAR) is used in the treatment of type B aortic dissections. Information related to aortic morphologic findings and the condition of the abdominal aorta after TEVAR is limited. OBJECTIVE To analyze aortic morphologic findings after TEVAR for type B aortic dissections. DESIGN, SETTING, AND PARTICIPANTS(More)
The main cause of mortality after the first year from cardiac transplantation is cardiac allograft vasculopathy (CAV), which leads to chronic rejection of the heart. To improve long-term outcomes in cardiac transplantation, treatments to prevent or diminish CAV are actively being researched. Ischemia-reperfusion (I-R) injury has been shown to be the(More)
BACKGROUND In this study we systematically dissect the prenylation pathway to better define the mechanism behind statin inhibition in chronic allograft rejection in heart transplants, or transplant coronary artery disease (TCAD). METHODS Utilizing a murine heterotopic heart transplant model, animals received daily treatments of either statin or selective(More)
OBJECTIVE The objective of this study was to determine the association of intraoperative completion imaging (CI) for lower extremity vein bypass to a below-knee target with primary patency in the Vascular Quality Initiative. METHODS The Vascular Quality Initiative database was queried from January 2003 to October 2013 for lower extremity bypass (LEB)(More)
Stroke is an exceedingly rare presentation of arterial thoracic outlet syndrome (aTOS). This report describes a case of cerebellar stroke secondary to aTOS and reviews the literature. A 56-year-old woman with no previous history of stroke or arm ischemia presented with vertigo. Computed tomography (CT) and magnetic resonance imaging confirmed a left(More)