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OBJECTIVE Cell therapy is an exciting area of investigation for repair of injured myocardial tissue. Platelet-rich plasma (PRP) is an autologous fractionation of whole blood containing high concentrations of growth factors including vascular endothelial growth factor and insulin-like growth factor, among many others. PRP has been shown to safely and(More)
OBJECTIVES Respiratory syncytial virus (RSV) is an important cause of upper respiratory infections and is known to play a causal role in the pathogenesis of rhinitis, sinusitis, acute otitis media, and pneumonia. RSV appears to prime the respiratory tract to secondary inciting events, such as bacterial or antigen challenges. To study the proinflammatory(More)
A 26-year-old man presented to a local emergency department with hematemesis and melena associated with mild mid-epigastric abdominal discomfort and light-headedness. He had no prior history of gastrointestinal (GI) bleeding, but he recalled having as a young child, up to 10 years of age, intermittent self-limited attacks of crampy abdominal pain that were(More)
The main cause of mortality after the first year from cardiac transplantation is cardiac allograft vasculopathy (CAV), which leads to chronic rejection of the heart. To improve long-term outcomes in cardiac transplantation, treatments to prevent or diminish CAV are actively being researched. Ischemia-reperfusion (I-R) injury has been shown to be the(More)
BACKGROUND In this study we systematically dissect the prenylation pathway to better define the mechanism behind statin inhibition in chronic allograft rejection in heart transplants, or transplant coronary artery disease (TCAD). METHODS Utilizing a murine heterotopic heart transplant model, animals received daily treatments of either statin or selective(More)
A 53-year-old woman presented with severe, post-prandial generalized abdominal pain and a 50-pound unintentional weight loss over a 3-month period. There had been a prior chronic history of this discomfort, but it had never reached this level of severity and it had not been associated with weight loss. Over the previous 3 months, her symptoms worsened to(More)
Stroke is an exceedingly rare presentation of arterial thoracic outlet syndrome (aTOS). This report describes a case of cerebellar stroke secondary to aTOS and reviews the literature. A 56-year-old woman with no previous history of stroke or arm ischemia presented with vertigo. Computed tomography (CT) and magnetic resonance imaging confirmed a left(More)
A 39-year-old man was admitted to our hospital with a chief complaint of progressively worsening abdominal pain over a 3-week period, characterized by a sharp midepigastric stabbing sensation radiating to his back. On admission, he was afebrile and hemodynamically stable. His abdominal examination elicited tenderness to palpation in the mid-epigastrium with(More)