Othman A. Al-Sagair

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Although the state of hyperhomocysteinemia (HHcy) appears to be associated with higher risks of coronary, cerebral and peripheral vascular disease as well as with a number of other clinical conditions, the underlying molecular mechanisms are not fully elucidated. There is strong evidence, however, that HHcy could induce a pathogenic state of oxidative(More)
The unwarranted connection between diabetes mellitus and breast cancer has gained new ground in recent years. Breast cancer in Saudi females accounts for approximately 21% of all cancers and the prevalence of diabetes mellitus (DM) in Saudi females is also 21.5%. DM is diagnosed in the age group of 30+ years with possible exposure to predisposing factors(More)
This study describes in silico validation of the wet lab data from aeroplysinin-1, curcumin and halofuginone using Autodock Tools 4.0. The inhibition patterns of the vascular endothelial cell differentiation and capillary tube formation mediated by anti-angiogenic growth factors from these test compounds were found quite comparable with the in silico(More)
Currently used hypolipidemic drugs, Fluvastatin and Atorvastatin, act via inhibiting the rate-limiting enzyme 3-hydroxy-3-methyl-glutaryl-coenzyme A (HMG-CoA) reductase of the mevalonate pathway. The associated severe side-effects of these statins led us to explore the therapeutic potentials of naturally occurring Tocomin (mixture of dietary α-, β-, γ- and(More)
The craniometric measurements in addition to the skull, cranial and facial indices undertaken in the immature and mature male Camelus dromedarius of the Malha phenotype (black) were: the skull length (35.99 cm), maximum width of neurocranium (11.33 cm), cranial length (15.45 cm), maximum zygomatic width (14.81 cm), viscerocranial length (20.55 cm), skull(More)
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