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In continuation of a project aimed at the structure-based design of drugs against sleeping sickness, analogs of 2'-deoxy-2'-(3-methoxybenzamido)adenosine (1) were synthesized and tested to establish… (More)
The diphenyl ester of the phosphonic acid analogue of proline and related dipeptides were prepared by a reaction of the corresponding N-substituted 4-aminobutyraldehyde and triphenyl phosphite.… (More)
The single-crystal X-ray structures of (-)-dimethyl[(2S)-1-(5,6,7,8- tetrahydro-5-oxonaphthalene-2-acetyl)piperidin-2-ylmethyl ]ammonium chloride, C20H29N2O2+.Cl-(BRL-53001A), and… (More)
The title compound, (C6H5CH2)3PO, is an organic tertiary phosphine oxide. The molecule has threefold symmetry, with the P—O bond along the threefold axis. Main dimensions include P—O 1.488 (4), P—C… (More)
Several 6-phenyl-3(2H)-pyridazinones bearing different alkenyl groups at position 5 have been prepared in the search for novel antiplatelet agents. The target compounds were synthesised by a… (More)