Osvaldo P Llanos

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Antibiotic therapy improves the outcome of severe sepsis and septic shock, however pharmacokinetic properties are altered in this scenario. Amikacin (AMK) is an option to treat community or nosocomial infections, although standard doses might be insufficient in critically ill patients. The aim of this study was to evaluate two AMK dosage regimens in(More)
RATIONALE Positive end-expiratory pressure (PEEP) and prone positioning may induce lung recruitment and affect alveolar dynamics in acute respiratory distress syndrome (ARDS). Whether there is interdependence between the effects of PEEP and prone positioning on these variables is unknown. OBJECTIVES To determine the effects of high PEEP and prone(More)
BACKGROUND Gallbladder diseases, especially cholelithiasis, are extremely frequent in Chile, and an increasing frequency of gallbladder carcinoma has been observed during the last decades. Hyperplastic and atypical epithelial lesions of gallbladder epithelium have been considered potential precursors of invasive carcinoma. The current study was designed to(More)
BACKGROUND Splenic abscesses are uncommon, appear in subjects with predisposing factors such as systemic infections and have high mortality rates. AIM To report seven patients with splenic abscesses. MATERIAL AND METHODS Retrospective review of medical records of patients with a splenic abscess treated between 1987 and 2005. RESULTS The records of(More)
The authors describe two cases that developed organizing pneumonia (OP) associated with novel influenza A(H1N1) virus. These patients were admitted to intensive care unit (ICU) because of severe respiratory failure. After initial clinical improvement, both patients worsened their condition during their second week of ICU stay, presenting fever, increasing(More)
OBJECTIVES The aim of the study was to evaluate the safety of extended prone position ventilation (PPV) and its impact on respiratory function in patients with severe acute respiratory distress syndrome (ARDS). DESIGN This was a prospective interventional study. SETTING Patients were recruited from a mixed medical-surgical intensive care unit in a(More)
BACKGROUND Septic shock is highly lethal. We recently implemented an algorithm (advanced resuscitation algorithm for septic shock, ARAS 1) with a global survival of 67%, but with a very high mortality (72%) in severe cases [norepinephrine (NE) requirements >0.3 microg/kg/min for mean arterial pressure > or =70 mmHg]. As new therapies with different levels(More)
UNLABELLED Bouveret syndrome is a duodenal obstruction caused by a biliary stone. AIM To report patients with Bouveret syndrome. MATERIAL AND METHODS Retrospective review of medical records of patients with Bouveret syndrome treated between 1976 and 2006. RESULTS We report three women and one man with a mean age of 62.5 years. None had a previous(More)
Management of patients with severe respiratory failure is mainly supportive, and protective mechanical ventilation is the pivotal treatment. When conventional therapy is insufficient to improve oxygenation without deleterious effects, other strategies should be considered. We report a 53 year-old male who presented a severe respiratory failure refractory to(More)
A 55 year old man presented with vomiting, abdominal pain, diarrhea, jaundice and choluria. An obstruction of the gastric outlet by a large gallstone located at the duodenum was demonstrated by radiologic, ultrasonographic and endoscopic examinations. The stone could not be removed through endoscopy and the patient was successfully operated on. A review of(More)