Ospan Mynbaev

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OBJECTIVE To develop a laparoscopic mouse model to evaluate the hypothesis that mesothelial hypoxia during pneumoperitoneum is a cofactor in adhesion formation. DESIGN Prospective randomized trials. SETTING Academic research center. ANIMAL(S) One hundred thirty female Naval Medical Research Institute (NMRI) mice. INTERVENTION(S) Adhesions were(More)
STUDY OBJECTIVE To investigate the effects of carbon dioxide (CO(2)) pneumoperitoneum-induced changes in blood gases, acid-base balance, and oxygen homeostasis in rabbits. DESIGN Prospective, randomized, controlled study (Canadian Task Force classification I). SETTING University training and teaching center. SUBJECTS Twenty-six adult female New(More)
BACKGROUND CO(2)-pneumoperitoneum used in endoscopic surgery induces system effects by CO(2) absorption. This study investigated the effect of the addition of O(2) to CO(2)-pneumoperitoneum, upon CO(2) absorption. METHODS The effect of a pneumoperitoneum using 100% CO(2) or 94% CO(2) + 6% O(2) upon arterial blood gases, acid base and O(2) homeostasis was(More)
Chronic hepatitis B (CHB) is a widespread infectious disease with unfavorable outcomes and life-threatening consequences for patients, in spite of modern vaccination and antiviral treatment modalities. Cutting-edge experimental approaches have demonstrated key pathways that involve cross-talk between viral particles and host immune cells. All events,(More)
Mother-to-child transmission (MTCT) of HBV is responsible for approximately half of the HBV transmission routes and continues to be a challenging problem worldwide. Even after the development of effective vaccines and clear World Health Organization guidelines toward HBV several decades ago, 1-9% newborns of HBV-carrying mothers still acquire HBV in early(More)
Authors evaluated the outcome of intracapsular cesarean myomectomy by a prospective case-control study on 68 patients who underwent intracapsular cesarean myomectomy, compared with a control group of 72 patients with myomatosic pregnant uterus who underwent cesarean section (CS) without myomectomy. Mostly of removed myomas were subserous or intramural,(More)
BACKGROUND Myomectomy is one of the most common surgical procedures in gynecology and has implications on fertility and subsequent pregnancies. We compared the impact of surgical approach on blood loss during laparoscopic and abdominal intracapsular myomectomy. MATERIAL AND METHODS The evaluation comprised 124 fertile women with subserous or intramural(More)
Fibroids or myomas involve large proportion of women of reproductive age. The myoma formation starts from the transformation of the myometrium, causing the progressive formation of a pseudocapsule, which is made of compressed muscle fibers. Numerous studies investigated on myoma pseudocapsule anatomy, discovering many neurotransmitters and neuropeptides, as(More)
Dear Sir, We read with great interest the article by Rajab et al. published in your journal in May 17, 2013. This article deals with one of the most problematic and unsettled issues in surgery. For more than 100 years, surgeons and researchers have studied the pathophysiology of postsurgical adhesions (PSAs) in order to prevent them, but its etiological(More)
With great interest we have read an article by Cağlar et al. [1], recently published in your journal. The authors aimed to present the impact of a gelatin–thrombin matrix application on postsurgical adhesion formation in a rat model. We are grateful for their attempt to shed some light on the impact of a gelatin–thrombin matrix application on postsurgical(More)