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BACKGROUND We previously found plasma levels of CD40 ligand (CD40L), chemokine (C-X-C motif) ligand 5 (CXCL5), chemokine (C-C motif) ligand 5 (CCL5) and epidermal growth factor (EGF) to be low in aplastic anemia (AA) patients and to be correlated with platelet count. OBJECTIVES To study the association of CD40L, CXCL5, CCL5 and EGF with platelets. (More)
The postnatal development of mediodorsal thalamic projections to the dorsomedial frontal cortex of mice was assessed by means of the retrograde peroxidase-colloidal gold complex tract tracing system. The tracer was injected into the dorsomedial frontal cortex from the day of birth (P0) to 60 days of postnatal age (P60). Since birth, a dense retrograde(More)
BACKGROUND The hydrolysis enzymes of the acetylcholine, acetylcholinesterase, and butyrylcholinesterase are involved in non-cholinergic functions such as proliferation processes and cellular adhesion. These enzymes have been found in several tumors other from brain tumors. METHODS Thirty fresh brain tumor specimens were obtained from biopsies taken during(More)
The distribution of acetylcholinesterase histochemistry and choline-O-acetyltransferase immunohistochemistry in the basal forebrain was studied in newborn mice (P0) and until 60 days of postnatal life (P60). A weak acetylcholinesterase activity was found at P0 and P2 in the anterior and intermediate parts of the basal forebrain, and higher in the posterior(More)
The topographical organization of the basal forebrain cholinergic projections to the frontal cortex in mice was assessed through acetylcholinesterase histochemistry and retrograde colloidal gold-wheat germ agglutinin-horseradish peroxidase double labeling. The anterior part of the magnocellular basal nucleus, and the horizontal limb of the diagonal band of(More)
The postnatal development of basal forebrain cholinergic projections to the medial prefrontal cortex in mice was analyzed by means of the double labeling track-tracing study. The tracer was injected into the medial prefrontal cortex of mice, on the day of birth (P0) to 60 days after birth. The total number of basal forebrain neurons increased from P4 to P8,(More)
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