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Transepithelial transport of Na(+) across the lung epithelium via amiloride-sensitive Na(+) channels (ENaC) regulates fluid volume in the lung lumen. Activators of AMP-activated protein kinase (AMPK), the adenosine monophosphate mimetic AICAR, and the biguanide metformin decreased amiloride-sensitive apical Na(+) conductance (G(Na+)) in human H441 airway(More)
I Acknowledgements I'd like to express my thanks to the many people who provided assistance or information during the course of this study, including: Oscar Mace for helping with research on ballast water laws and ballast water sampling programs. in Seattle) for patiently answering my many questions and providing me with needed documents. Herbert(More)
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