Oscar Fernández

Guillermo Izquierdo9
Rafael Arroyo6
9Guillermo Izquierdo
6Rafael Arroyo
4Elena Urcelay
4David Brassat
4Laura Leyva
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This paper presents a system providing functionalities for cataloging multimedia content using MPEG-7 and accessing to content and descriptions. The cataloging application indexes content using MPEG-7 and creates annotated variations in order to have the capability of offering media content to a large amount of different terminals and through different(More)
BACKGROUND IL-2 receptor (IL2R) alpha is the specific component of the high affinity IL2R system involved in the immune response and in the control of autoimmunity. METHODS AND RESULTS Here we perform a replication and fine mapping of the IL2RA gene region analyzing 3 SNPs previously associated with multiple sclerosis (MS) and 5 SNPs associated with type(More)
  • Belén de la Hera, Jezabel Varadé, Marta García-Montojo, Antonio Alcina, María Fedetz, Iraide Alloza +10 others
  • 2014
BACKGROUND Human endogenous retroviruses (HERVs) are repetitive sequences derived from ancestral germ-line infections by exogenous retroviruses and different HERV families have been integrated in the genome. HERV-Fc1 in chromosome X has been previously associated with multiple sclerosis (MS) in Northern European populations. Additionally, HERV-Fc1 RNA(More)
Multiple Sclerosis (MS) is the most common progressive and disabling neurological condition affecting young adults in the world today. From a genetic point of view, MS is a complex disorder resulting from the combination of genetic and non-genetic factors. We aimed to identify previously unidentified loci conducting a new GWAS of Multiple Sclerosis (MS) in(More)
Radial Basis Neural Networks (RBNN) can approximate any regular function and have a faster training phase than other similar neu-ral networks. However, the activation of each neuron depends on the euclidean distance between a pattern and the neuron center. Therefore, the activation function is symmetrical and all attributes are considered equally relevant.(More)
The design, implementation, and test of a real-time flexible 2×2 (Multiple Input Multiple Output-Orthogonal Frequency Division Multiplexing) MIMO-OFDM IEEE 802.16 prototype are presented. For the design, a channel measurement campaign on the 3.5 GHz band has been carried out, focusing on outdoor-indoor scenarios. The analysis of measured channels showed(More)
  • Oscar Fernández, Javier Agüera, Guillermo Izquierdo, Javier Millán-Pascual, Lluis Ramió i Torrentà, Pedro Oliva +6 others
  • 2012
BACKGROUND Adherence to interferon β-1b (INFβ-1b) therapy is essential to maximize the beneficial effects of treatment in multiple sclerosis (MS). For that reason, the main objectives of this study are to assess adherence to INFβ-1b in patients suffering from MS in Spain, and to identify the factors responsible for adherence in routine clinical practice. (More)
Objective: To evaluate the effects of oral delayed-release dimethyl fumarate (DMF; also known as gastro-resistant DMF) on MRI lesion activity and load, atrophy, and magnetization transfer ratio (MTR) measures from the Comparator and an Oral Fumarate in Relapsing-Remitting Multiple Sclerosis (CONFIRM) study. Methods: CONFIRM was a 2-year, placebo-controlled(More)