Oscar Caballero

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Cell surface proteins are excellent targets for diagnostic and therapeutic interventions. By using bioinformatics tools, we generated a catalog of 3,702 transmembrane proteins located at the surface of human cells (human cell surfaceome). We explored the genetic diversity of the human cell surfaceome at different levels, including the distribution of(More)
A gene, HDC1, related to the Saccharomyces cerevisiae histone deacetylase (HDAC) gene HOS2, was isolated from the filamentous fungus Cochliobolus carbonum, a pathogen of maize that makes the HDAC inhibitor HC-toxin. Engineered mutants of HDC1 had smaller and less septate conidia and exhibited an approximately 50% reduction in total HDAC activity. Mutants(More)
We describe and demonstrate CBGIR, a web-based system for performing content-based image retrieval in large sets of high-resolution overhead images. The system provides a familiar Google Maps interface to navigate the images and select regions of interest. A query-by-example paradigm is used to retrieve the most visually similar images to this region from a(More)
Lower limb lymphorrhea secondary to a surgical procedure is a rare but difficult-to-solve complication. In lower limb, this entity is frequently associated with vascular procedures around the inguinal area. We report on a case of a knee lymphocutaneous fistula secondary to a knee revision arthroplasty. To our knowledge, no previous reports regarding this(More)
We describe and demonstrate CBGIR, a web-based system for performing content-based image retrieval in large sets of high-resolution overhead images. The system provides a familiar Google Maps interface to navigate the images and select regions of interest. A query-by-example paradigm is used to retrieve the most visually similar images to this region from a(More)
INTRODUCTION Global amnesia (AG) is a dysfunction of memory, in which there is a sudden incapacity to remember recent events and assimilate new information. The aetiology is currently under discussion. The main hypotheses under consideration are an ischemic mechanism and an epileptic mechanism. OBJECTIVE To study the cerebral blood flow in patients with(More)
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