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BACKGROUND Obesity has been associated with impaired endothelial function, but the influence of lifetime weight patterns on endothelial function has not been studied. HYPOTHESIS We hypothesized that coronary vascular reactivity would be diminished in postmenopausal women with a history of obesity and frequent weight swings. METHODS We performed dynamic(More)
Positron emission tomography (PET) myocardial perfusion imaging has higher spatial resolution than conventional single photon emission computed tomography (SPECT) imaging and allows accurate and reproducible quantification of myocardial blood flow (MBF). In this article, we describe the role of PET myocardial perfusion imaging in clinical decision making in(More)
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