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BACKGROUND The ideal closure technique of the pancreas after distal pancreatectomy is unknown. We postulated that standardised closure with a stapler device would prevent pancreatic fistula more effectively than would a hand-sewn closure of the remnant. METHODS This multicentre, randomised, controlled, parallel group-sequential superiority trial was done(More)
BACKGROUND A commercially available nanocrystalline hydroxyapatite paste Ostim has been reported in few recent studies to surpass other synthetic bone substitutes with respect to the observed clinical results. However, the integration of this implantable material has been histologically evaluated only in animal experimental models up to now. This study(More)
BACKGROUND The concept of total mesorectal excision has revolutionised rectal cancer surgery. TME reduces the rate of local recurrence and tumour associated mortality. However, in clinical trials only 50% of the removed rectal tumours have an optimal TME quality. PATIENTS During a period of 36 months we performed 103 rectal resections. The majority of(More)
The use of nanoparticles for optical strorage of information is reviewed. Several different optical recording media utilizing the nanoparticles were designed and tested. The main characteristics of the media, namely, density of recording energy needed and density of stored information start from the like ones for blu-ray disk and for the best media are far(More)
BACKGROUND This study aimed to analyse the most common current indications for total pancreatectomy (TP) at a high-volume pancreas center. METHOD Prospectively collected data on indications and short-term outcome of all TP's performed from January 2004 until June 2008 were analysed. RESULTS The total pancreatectomies (TP) were 63, i.e., 6.7% of all(More)
BACKGROUND Animal experiments on hernia repair demonstrated better biocompatibility of light-weight polypropylene meshes. However, implanted medical devices trigger a variety of adverse tissue responses, such as inflammation, fibrosis, infection and thrombosis, but the mechanisms involved in such responses remain largely unknown. This study aimed to(More)
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