Learn More
Atherosclerotic disease of the renal artery can lead to reduction in arterial caliber and ultimately to conditions including renovascular hypertension. Renal artery stenosis is conventionally assessed, using angiography, according to the severity of the stenosis. However, the severity of a stenosis is not a reliable indicator of functional significance, or(More)
RATIONALE AND OBJECTIVES The authors' goal was to develop a noninvasive method for detailed assessment of blood flow patterns from direct in vivo measurements of vessel anatomy and flow rates. MATERIALS AND METHODS The authors developed a method to construct realistic patient-specific finite element models of blood flow in carotid arteries. Anatomic(More)
Colloidal suspensions of iron oxide magnetic nanoparticles are known to dissipate energy when exposed to an oscillating magnetic field. Such energy dissipation can be employed to locally raise temperature inside a tumor between 41°C and 45°C (hyperthermia) to promote cell death, a treatment known as magnetic fluid hyperthermia (MFH). This work seeks to(More)
Computational fluid dynamics (CFD) models of the carotid artery are constructed from contrast-enhanced magnetic resonance angiography (MRA) using a deformable model and a surface-merging algorithm. Physiologic flow conditions are obtained from cine phase-contrast MRA at two slice locations below and above the carotid bifurcation. The methodology was tested(More)
This paper summarizes the major improvements and developments that have taken place during the last year for FEFLO, a general-purpose CFD code based on adaptive, unstructured grids. All aspects of a comprehensive CFD capability: gridding, solvers, mesh movement techniques, eective use of supercomputer architectures and design saw important a d v ances, and(More)
Magnetic fluid hyperthermia as a cancer treatment method is an attractive alternative to other forms of hyperthermia. It is based on the heat released by magnetic nanoparticles subjected to an alternating magnetic field. Recent studies have shown that magnetic fluid hyperthermia-treated cells respond significantly better to chemotherapeutic treatment(More)
Studies on hexose consumption by Saccharomyces cerevisiae show that glucose is consumed faster than fructose when both are present (9:1 fructose to glucose) in the medium during the fermentation of Agave. The objective of this work was to select strains of S. cerevisiae that consume fructose equal to or faster than glucose at high fructose concentrations by(More)