Orlando Soto

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Atherosclerotic disease of the renal artery can lead to reduction in arterial caliber and ultimately to conditions including renovascular hypertension. Renal artery stenosis is conventionally assessed, using angiography, according to the severity of the stenosis. However, the severity of a stenosis is not a reliable indicator of functional significance, or(More)
This paper summarizes the major improvements and developments that have taken place during the last year for FEFLO, a general-purpose CFD code based on adaptive, unstructured grids. All aspects of a comprehensive CFD capability: gridding, solvers, mesh movement techniques, eective use of supercomputer architectures and design saw important a d v ances, and(More)
Colloidal suspensions of iron oxide magnetic nanoparticles are known to dissipate energy when exposed to an oscillating magnetic field. Such energy dissipation can be employed to locally raise temperature inside a tumor between 41°C and 45°C (hyperthermia) to promote cell death, a treatment known as magnetic fluid hyperthermia (MFH). This work seeks to(More)
Computational fluid dynamics (CFD) models of the carotid artery are constructed from contrast-enhanced magnetic resonance angiography (MRA) using a deformable model and a surface-merging algorithm. Physiologic flow conditions are obtained from cine phase-contrast MRA at two slice locations below and above the carotid bifurcation. The methodology was tested(More)
Magnetic fluid hyperthermia as a cancer treatment method is an attractive alternative to other forms of hyperthermia. It is based on the heat released by magnetic nanoparticles subjected to an alternating magnetic field. Recent studies have shown that magnetic fluid hyperthermia-treated cells respond significantly better to chemotherapeutic treatment(More)
Two design methodologies based on Incomplete-Gradient ad-joint approaches for ow problems governed by the incom-pressible Navier-Stokes (NS) equations are presented. The main features of the algorithms is that they avoid solving the adjoint equations, saving an important a m o u n t of CPU time. Furthermore, the methodologies are general in the sense that(More)
A design methodology based on a mixed adjoint a p p r o a c h for ow problems governed by the Incompressible Turbulent N a vier Stokes equations is deduced and tested. The main feature of the algorithm is that instead of solving an exact discrete adjoint equation, it solves a fast-converging low-order adjoint formulation, saving an important amount of CPU(More)
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