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APOBEC3 proteins catalyze deamination of cytidines in single-stranded DNA (ssDNA), providing innate protection against retroviral replication by inducing deleterious dC > dU hypermutation of replication intermediates. APOBEC3G expression is induced in mitogen-activated lymphocytes; however, no physiologic role related to lymphoid cell proliferation has yet(More)
1Department of Pathology and the Lautenberg Center for General and Tumor Immunology, Hebrew University–Hadassah Medical School, Jerusalem, Israel; 2Institute of Chemistry and Center for Nanoscience and Nanotechnology, Hebrew University, Jerusalem, Israel; 3Department of Genetics, Institute of Life Sciences, Hebrew University, Jerusalem, Israel; 4Division of(More)
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