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Practical application of genomic-based risk stratification to clinical diagnosis is appealing yet performance varies widely depending on the disease and genomic risk score (GRS) method. Celiac… (More)
- Gad Abraham, Aki S. Havulinna, +12 authors Michael Inouye
- 2016
Background Genetics plays an important role in coronary heart disease (CHD) but the clinical utility of a genomic risk score (GRS) relative to clinical risk scores, such as the Framingham Risk Score… (More)
Coronary artery disease (CAD) is a complex disease driven by myriad interactions of genetics and environmental factors. Traditionally, studies have analyzed only one disease factor at a time,… (More)
- Oneil G Bhalala, Artika P Nath, Michael Inouye, Christopher R. Sibley
- PLoS genetics
- 2018
Schizophrenia and the affective disorders, here comprising bipolar disorder and major depressive disorder, are psychiatric illnesses that lead to significant morbidity and mortality worldwide. Whilst… (More)
- Gad Abraham, Jason A. Tye-Din, Oneil G Bhalala, Adam Kowalczyk, Justin Zobel, Michael Inouye
- PLoS genetics
- 2014
Practical application of genomic-based risk stratification to clinical diagnosis is appealing yet performance varies widely depending on the disease and genomic risk score (GRS) method. Celiac… (More)
Schizophrenia and the affective disorders, here comprising bipolar disorder and major depressive disorder, are psychiatric illnesses that lead to significant morbidity and mortality worldwide. Whilst… (More)
- Gad Abraham, Oneil G Bhalala, Paul I W de Bakker, Samuli Ripatti, Michael Inouye
- Current Cardiology Reports
- 2014
Coronary artery disease (CAD) is a complex disease driven by myriad interactions of genetics and environmental factors. Traditionally, studies have analyzed only 1 disease factor at a time, providing… (More)
- Gad Abraham, Aki S. Havulinna, +12 authors Michael Inouye
- European heart journal
- 2016
AIMS
Genetics plays an important role in coronary heart disease (CHD) but the clinical utility of genomic risk scores (GRSs) relative to clinical risk scores, such as the Framingham Risk Score (FRS),… (More)