Omneya Ibrahim Youssef

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Cardiac arrest has been described in children with diabetic ketoacidosis (DKA). Aim. To evaluate QTc and QTd in type 1 diabetic children with DKA. Methods. Twelve-lead ECG was done to 30 type 1 diabetic children with DKA at presentation and recovery. Corrected QT interval and QT dispersion (QTd) were assessed. Results. QTc and QTd mean values were(More)
Platelet microparticles (PMPs) and function profile in children with congenital heart disease (CHD) have not been widely explored. We investigated platelet aggregation, flow cytometric platelet surface receptors (P-selectin and glycoprotein (GP) IIb/IIIa) and PMPs in 23 children with cyanotic CHD (CCHD), 30 children with acyanotic CHD (ACHD) and 30 healthy(More)
OBJECTIVE To evaluate adiponectin levels in children and adolescents with type I diabetes, and their relationship to long term complications. DESIGN Cross sectional. SETTING Tertiary referral hospital, Cairo, Egypt. PARTICIPANTS Thirty children and adolescents with type I diabetes mellitus, classified into complicated and non-complicated and compared(More)
BACKGROUND Carotid intima media thickness (CIMT) is a non invasive marker of subclinical atherosclerosis. Hyperglycemia, oxidatively modified atherogenic lipoproteins and advanced glycation end products are linked to increased oxidative stress in diabetes. We aimed to find out the relation between carotid intima media thickness in type 1 diabetic children(More)
Dilated cardiomyopathy is an important cause of congestive cardiac failure in infants and children. Mobilizing hematopoietic progenitor cells is a promising intervention to this deadly disease. Aim. Evaluate granulocyte colony stimulating factor (GCSF) as therapeutic modality in children with idiopathic dilated cardiomyopathy (IDCM). Subjects and Methods.(More)
Congenital heart defects (CHDs) are among the most common birth defects. The majority of CHDs are polygenic diseases affected by both genetic and environmental factors. Identification of the candidate genes in folate metabolism has suggested that the 677C→T polymorphism in the Methylenetetrahydrofolate reductase (MTHFR) gene may be particularly associated(More)
BACKGROUND Dysfunction of the autonomous nervous system causes arrhythmias and, although previous studies have investigated the effects of epilepsy on the autonomic control of the heart, there is still uncertainty about whether imbalance of sympathetic, vagal, or both systems occurs in epilepsy as well as the effect of anticonvulsants on the autonomic(More)
Endothelial damage has been implicated in the pathogenesis of vascular complications in β-thalassemia intermedia (β-TI). Soluble fms-like tyrosine kinase 1 (sFLT-1) is a member of the vascular endothelial growth factor receptor (VEGFR) family. Soluble fms-like tyrosine kinase 1 is an antiangiogenic protein that induces endothelial dysfunction by adhering to(More)
BACKGROUND Heart disease is the leading cause of mortality and one of the main causes of morbidity in β-thalassemia. Growth differentiation factor-15 (GDF-15), a member of the transforming growth factor-β superfamily, is a marker of ineffective erythropoiesis in several anemias. AIM To determine GDF-15 levels in children and adolescents with TI and the(More)
Introduction In the era of regenerative medicine and cell-based therapies, endothelial progenitor cells [EPC] attracted many researches as they represent one subtype of bone marrow derived cells that were shown to be able to replace old damaged endothelial cells by forming a patch that heals the endothelium after its injury [1]. The release of EPCs from the(More)