Olusegun O Osinbowale

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Venous thromboembolism (VTE), including deep vein thrombosis (DVT) and pulmonary embolism, represents a significant source of morbidity and mortality. It is readily diagnosed with noninvasive modalities when there is a clinical suspicion. Most patients presenting with signs and symptoms of DVT have well-known risk factors, such as a history of VTE,(More)
Rectus sheath hematoma (RSH) is a known complication of anticoagulation therapy and a source of potential morbidity and mortality. Early diagnosis and appropriate treatment may help to prevent complications including hemodynamic instability, the abdominal compartment syndrome or multiorgan dysfunction. Although the diagnosis can be made clinically, it can(More)
Peripheral artery disease (PAD) is a major health problem worldwide, affecting millions of patients. Although cardiovascular risk factors such as diabetes mellitus, tobacco abuse, hypertension, and hypercholesterolemia have been associated with the development of PAD, the possible existence of an inherited genetic predisposition to PAD has been investigated(More)
Peripheral arterial disease (PAD) is a common disorder caused largely by atherosclerosis. Although it is associated with increased morbidity and cardiovascular mortality, PAD remains underdiagnosed. Traditional PAD care has involved cardiovascular risk factor modification, use of antiplatelet agents, and revascularization. For those individuals who are(More)
Some patients need higher-than-expected doses of warfarin (Coumadin) to get their international normalized ratio (INR) into the therapeutic range. The cause of warfarin resistance can be either acquired (eg, poor compliance, drug interactions, dietary interactions) or hereditary, but the genetic mechanisms of warfarin resistance are not well understood.(More)
Descending thoracic aortic aneurysms, similar to other aneurysms, are often incidentally diagnosed in patients with unrelated complaints. Management of these aneurysms is largely dependent on their size and anatomy. Most individuals with asymptomatic descending thoracic aortic aneurysms may be safely managed with cardiovascular risk factor modification(More)
Pharmacologic interventions are an integral component of peripheral artery disease (PAD) management, supported by high-quality clinical studies. Those affected by this potentially debilitating and life-threatening disease process often have multiple contributing conditions, such as tobacco abuse, diabetes, hypertension, and hyperlipidemia. In addition to(More)
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