Olufemi Williams

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OBJECTIVES Zidovudine (ZDV) requires intracellular phosphorylation to ZDV triphosphate (ZDV-TP) prior to the inhibition of HIV replication. The effect of ZDV dose on the formation of intracellular phosphorylated metabolites may help define the optimum daily dose of ZDV, which is still unknown. DESIGN AND METHODS The plasma and intracellular phosphorylated(More)
The present study of 47 necropsy cases of congenital heart disease has revealed that cardiac defects occur as frequently in the African as in the non-African. The types of congenital heart disease and the associated non-cardiac malformations are similar to what has been described in non-Africans. Tetrad of Fallot was the commonest type of multiple defect(More)
i h fi t t ifurcation lesions remain an unresolved problem for perutaneous coronary intervention (PCI). Broadly defined as tenoses that involve the origin of an arterial side branch xceeding 2.0 mm in diameter, bifurcation lesions present a hallenge to achieve relief of arterial narrowing, deliver nterventional devices including balloon catheters and tents,(More)
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