Olubunmi Victoria Akinpelu

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OBJECTIVE To investigate possible ototoxic effects of a one-time application of oxymetazoline drops in a chinchilla animal model with tympanostomy tubes. Study Design. A prospective, controlled animal study. SETTING The Research Institute of the Montreal's Children Hospital, McGill University Health Centre. SUBJECTS AND METHODS Ventilation tubes were(More)
OBJECTIVES/HYPOTHESIS The aim of this study was to systematically and quantitatively review the available evidence on the effects of type 2 diabetes mellitus on hearing function. DATA SOURCES AND REVIEW METHODS Eligible studies were identified through searches of eight different electronic databases and manual searching of references. Articles obtained(More)
BACKGROUND AND OBJECTIVES Otoacoustic emission (OAE) tests are currently used to screen newborns for congenital hearing loss in many Universal Newborn Hearing Screening programs. However, there are concerns about high referral and false-positive rates. Various protocols have been used to address this problem. The main objective of this review is to(More)
OBJECTIVES Cisplatin, one of the most effective and widely used chemotherapeutic agents in the treatment of head and neck malignancies, has severe dose-limiting side effects including ototoxicity. This study evaluates the effectiveness of nanoencapsulated curcumin and dexamethasone in preventing degenerative changes in inner ear cells caused by cisplatin.(More)
In this prospective controlled animal study, the authors investigated the potential ototoxic effects of ototopical application of nystatin through a tympanostomy tube, using their established chinchilla animal model. Each of the 10 animals used had ventilation tubes inserted in both ears; 1 ear was randomly assigned to receive nystatin suspension, whereas(More)
We present a case of multiple degloving injuries in an elderly man following a fall from a palm tree. Multiple midface injuries are very rare, although individual types have been reported. Our patient sustained injuries in the lower and middle thirds of the face, including multiple tongue lacerations and a deep jagged laceration at the lower posterior part(More)
BACKGROUND The pathologic changes that occur as a result of diabetic microangiopathy have been well described for the kidneys and the eyes. Although many studies suggest an association between diabetes mellitus and hearing loss, the pathologic changes in the cochlea in association with the diabetic state remain to be clarified. AIM/OBJECTIVE The aim of(More)
OBJECTIVES High levels of unconjugated bilirubin have been associated with neuronal damage. The auditory brain nuclei and the inferior colliculi are often the first part of the brainstem to be involved, often leading to hearing abnormalities. A systematic review of clinical studies was conducted to evaluate the effect of hyperbilirubinemia on hearing in(More)
The maxillofacial unit is an uncommon entry point for cases of nasopharyngeal carcinoma (NPC). This report documents involvement of the maxillofacial unit in the management of NPC in Obafemi Awolowo University Teaching Hospitals Complex, Ile-lfe, Nigeria, with the aim of highlighting the challenges associated with recognition and management of the disease.(More)
OBJECTIVE Acute mastoiditis is an uncommon but challenging condition when it occurs in children with cochlear implant. The literature is scarce as to the management of this condition with regards to explantation. The objective of the study is to determine the need for explantation in patients with cochlear implants who suffer from acute mastoiditis. DATA(More)