Olli Sippula

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Multiple studies show that particulate mass (PM) generated from incomplete wood combustion may induce adverse health issues in humans. Previous findings have shown that also the PM from efficient wood combustion may induce enhanced production of reactive oxygen species (ROS), inflammation, and cytotoxicity in vitro and in vivo. Underlying factors of these(More)
The chemical composition of particulate matter (PM) emissions from a medium-speed four-stroke marine engine, operated on both heavy fuel oil (HFO) and distillate fuel (DF), was studied under various operating conditions. PM emission factors for organic matter, elemental carbon (soot), inorganic species and a variety of organic compounds were determined. In(More)
BACKGROUND Ship engine emissions are important with regard to lung and cardiovascular diseases especially in coastal regions worldwide. Known cellular responses to combustion particles include oxidative stress and inflammatory signalling. OBJECTIVES To provide a molecular link between the chemical and physical characteristics of ship emission particles(More)
Catalytic converters can be used to decrease carbon monoxide, organic compounds and soot from small-scale wood-fired appliances. The reduction is based on the oxidation of gaseous and particulate pollutants promoted by catalytic transition metal surfaces. However, many transition metals have also strong catalytic effect on PCDD/F formation. In this study(More)
The performance of four sampling devices for inhalable dust and three devices for respirable dust was tested with different kinds of dusts in the laboratory and in the field. The IOM sampler was chosen as the reference method for inhalable dust, and the IOM sampler provided with the porous plastic foam media was used as the reference method for respirable(More)
Ambient air particulate matter (PM) is increasingly considered to be a causal factor evoking severe adverse health effects. People spend the majority of their time indoors, which should be taken into account especially in future risk assessments, when the role of outdoor air particles transported into indoor air is considered. Therefore, there is an urgent(More)
Several studies have shown that combustion-derived fine particles cause adverse health effects. Previous toxicological studies on combustion-derived fine particles have rarely involved multiple endpoints and a detailed characterization of chemical composition. In this study, we developed a novel particle sampling system for toxicological and chemical(More)
Ambient air particulate matter (PM) as well as microbial contaminants in the indoor air are known to cause severe adverse health effects. It has been shown that there is a clear seasonal variation in the potency of outdoor air particles to evoke inflammation and cytotoxicity. However, the role of outdoor sources in the indoor air quality, especially on its(More)
Organic combustion aerosols from a marine medium-speed diesel engine, capable to run on distillate (diesel fuel) and residual fuels (heavy fuel oil), were investigated under various operating conditions and engine parameters. The online chemical characterisation of the organic components was conducted using a resonance-enhanced multiphoton ionisation(More)
Significant amounts of transition metals such as zinc, cadmium and copper can become enriched in the fine particle fraction during biomass combustion with Zn being one of the most abundant transition metals in wood combustion. These metals may have an important role in the toxicological properties of particulate matter (PM). Indeed, many epidemiological(More)