Olivier Boiron

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A penalization method is applied to model the interaction of large Mach number compressible flows with obstacles. A supplementary term is added to the compressible Navier-Stokes system, seeking to simulate the effect of the Brinkmanpenalization technique used in incompressible flow simulations including obstacles. We present a computational study comparing(More)
A 2-D finite element model for the intervertebral disc in which quadriphasic theory is coupled to the transport of solutes involved in cellular nutrition was developed for investigating the main factors contributing to disc degeneration. Degeneration is generally considered to result from chronic disc cell nutrition insufficiency, which prevents the cells(More)
Using the finite element method, physiological blood flows through a three-dimensional model of a coronary graft are numerically analysed. The model includes a stenosis shape in the host artery upstream from the anastomosis. Recirculating areas, secondary flows, wall shear stress (WSS) and spatial wall shear stress gradients (WSSGs) are studied for(More)
OBJECTIVES The aim was to analyze the role played by anatomy and stent graft in the incidence of incomplete apposition to aortic arch. METHODS Between 2007 and 2014 data including available and suitable computed tomographic angiography (CTA) imaging of patients who had undergone thoracic endovascular aortic repair were reviewed. The study included 80(More)
A new experimental setup has been implemented to precisely measure the deformations of an entire model abdominal aortic aneurysm (AAA). This setup addresses a gap between the computational and experimental models of AAA that have aimed at improving the limited understanding of aneurysm development and rupture. The experimental validation of the deformations(More)
Ethylene glycol ethers and their acetate derivatives were analyzed for their toxicity in vitro on several hemopoietic cell lines, either growth-factor-dependent or leukemic, in mouse, rat, and human species. Considering the concentrations that reduced the cell viability in culture by 50%, most of the ethylene glycol ethers and in particular ethylene glycol(More)
Advantages of inhaled therapies as a priori targeted supply of drugs make them particularly convenient for the treatment of lung diseases. Nevertheless, several physical and anatomical factors can largely influence treatment efficiency. In particular, upper airways (UA) anatomic arrangement acts as an unwanted filter, which limits the amount of drug(More)
One of the aims of this work is to develop an original custom built biaxial set-up to assess mechanical behavior of soft tissues. Stretch controlled biaxial tensile tests are performed and stereoscopic digital image correlation (SDIC) is implemented to measure the 3D components of the generated displacements. Using this experimental device, the main goal is(More)
OBJECTIVE The present study aimed at quantifying mal-positioning during thoracic endovascular aortic repair and analysing the extent to which anatomical factors influence the exact stent graft positioning. METHODS A retrospective review was conducted of patients treated between 2007 and 2014 with a stent graft for whom proximal landing zones (LZ) could be(More)