Olivier Bibari

Tracey C Dickson2
Anna E King2
James C Vickers2
Jerome A Staal2
2Tracey C Dickson
2Anna E King
2James C Vickers
2Jerome A Staal
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  • James C Vickers, Anna E King, Adele Woodhouse, Matthew T Kirkcaldie, Jerome A Staal, Graeme H McCormack +7 others
  • 2009
There has been growing interest in the axon as the initial focus of pathological change in a number of neurodegenerative diseases of the central nervous system. This review concentrates on three major neurodegenerative conditions--amyotrophic lateral sclerosis, multiple sclerosis and Alzheimer's disease--with emphasis on key cellular changes that may(More)
The neurofilament light (NFL) subunit is considered as an obligate subunit polymer for neuronal intermediate filaments comprising the neurofilament (NF) triplet proteins. We examined cytoskeletal protein levels in the cerebral cortex of NFL knockout (KO) mice at postnatal day 4 (P4), 5 months, and 12 months of age compared with age-matched wild-type (WT)(More)
The effect of miniaturizing the electrode lead for Deep Brain Stimulation (DBS) therapy was investigated in this work. A direct comparison was made between a miniature lead (0.65 mm diameter) and a lead of standard size (1.3 mm). Acute in vivo implantation in two cat brains was performed to evaluate surgical trauma and confirm capacity to target thalamic(More)
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