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Emergence and spread of a human-transmissible multidrug-resistant nontuberculous mycobacterium
Global spread of aggressive mycobacteria Many mycobacteria, in addition to those causing leprosy and tuberculosis, are capable of infecting humans. Some can be particularly dangerous in patients… Expand
Endobronchial valve placement for the treatment of bronchopleural fistula: a review of the current literature
Purpose of review Bronchopleural fistula is a cause of increased morbidity and mortality. Patients who develop bronchopleural fistula after lung resection or spontaneous pneumothorax often have… Expand
Mapping targetable inflammation and outcomes with cystic fibrosis biomarkers
Cystic fibrosis is characterized by an overly exuberant neutrophilic inflammatory response to pathogens and other stimuli that starts very early in disease. The overwhelming nature of this response… Expand
Outcomes associated with antibiotic regimens for treatment of Mycobacterium abscessus in cystic fibrosis patients.
- A. DaCosta, C. Jordan, Olivia Giddings, Feng-Chang Lin, P. Gilligan, C. Esther
- Journal of cystic fibrosis : official journal of…
- 1 July 2017
BACKGROUND Mycobacterium abscessus infection is associated with declining lung function in cystic fibrosis (CF), but there is little evidence on clinical efficacy to guide treatment. METHODS… Expand
A treatment that eliminates SARS-CoV-2 replication in human airway epithelial cells and is safe for inhalation as an aerosol in healthy human subjects.
BACKGROUND Low airway surface pH is associated with many airway diseases, impairs antimicrobial host defense and worsens airway inflammation. Inhaled Optate is designed to safely to raise airway… Expand