Oliver Yenjyh Chen

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The use of heat as a means of treatment for various diseases dates back to very ancient times. A well-known Greek philosopher and scientist Hippocrates (c. 460 – c. 370 BC), who is considered as the ‘father of medicine,’ stated that a disease must be incurable if it could not be cured by using heat. He even went on to successfully treat breast tumors with(More)
Measuring temperature in nanoscale spatial resolution either at or far from equilibrium is of importance in many scientific and technological applications. Although negatively charged nitrogen-vacancy (NV(-)) centers in diamond have recently emerged as a promising nanometric temperature sensor, the technique has been applied only under steady state(More)
Recent advances in quantum technology have demonstrated the potential use of negatively charged nitrogen-vacancy (NV) centers in diamond for temperature and magnetic sensing at sub-cellular levels. Fluorescent nanodiamonds (FNDs) containing high-density ensembles of NV centers are appealing for such applications because they are inherently biocompatible and(More)
Nanodiamonds containing high density ensembles of negatively charged nitrogen-vacancy (NV(-)) centers are promising fluorescent biomarkers due to their excellent photostability and biocompatibility. The NV(-) centers in the particles have a fluorescence lifetime of up to 20 ns, which distinctly differs from those (<10 ns) of cell and tissue(More)
Much of the current understanding of thermal effects in biological systems is based on macroscopic measurements. There is little knowledge about the local thermostability or heat tolerance of subcellular components at the nanoscale. Herein, we show that gold nanorod-fluorescent nanodiamond (GNR-FND) hybrids are useful as a combined(More)
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