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  • Gretel Buchwald, Petra P M van der Stoop, Oliver Weichenrieder, Anastassis Perrakis, Maarten van Lohuizen, Titia K. Sixma
  • Biology, Medicine
  • The EMBO journal
  • 2006 (First Publication: 7 June 2006)
  • Polycomb group proteins Ring1b and Bmi1 (B-cell-specific Moloney murine leukaemia virus integration site 1) are critical components of the chromatin modulating PRC1 complex. Histone H2AExpand
  • Felix Tritschler, Joerg E Braun, Ana Eulalio, Vincent Truffault, Elisa Izaurralde, Oliver Weichenrieder
  • Medicine, Biology
  • Molecular cell
  • 2009 (First Publication: 1 March 2009)
  • The DEAD box helicase DDX6/Me31B functions in translational repression and mRNA decapping. How particular RNA helicases are recruited specifically to distinct functional complexes is poorlyExpand
  • Joerg E Braun, Vincent Truffault, +6 authors Elisa Izaurralde
  • Biology, Medicine
  • Nature Structural &Molecular Biology
  • 2012 (First Publication: 1 December 2012)
  • The removal of the mRNA 5′ cap structure by the decapping enzyme DCP2 leads to rapid 5′→3′ mRNA degradation by XRN1, suggesting that the two processes are coordinated, but the coupling mechanism isExpand
  • Evelyn Sauer, Steffen Schmidt, Oliver Weichenrieder
  • Medicine, Biology
  • Proceedings of the National Academy of Sciences
  • 2012 (First Publication: 29 May 2012)
  • The bacterial Sm-like protein Hfq is a central player in the control of bacterial gene expression. Hfq forms complexes with small regulatory RNAs (sRNAs) that use complementary “seed” sequences toExpand
  • Alain-Pierre Petit, Lara Wohlbold, +4 authors Oliver Weichenrieder
  • Medicine, Biology
  • Nucleic acids research
  • 2012 (First Publication: 12 September 2012)
  • The CCR4–NOT complex plays a crucial role in post-transcriptional mRNA regulation in eukaryotic cells. It catalyzes the removal of mRNA poly(A) tails, thereby repressing translation and committingExpand
  • Andreas Boland, Eric Huntzinger, Steffen Schmidt, Elisa Izaurralde, Oliver Weichenrieder
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences
  • 2011 (First Publication: 6 June 2011)
  • Argonaute proteins (AGOs) are essential effectors in RNA-mediated gene silencing pathways. They are characterized by a bilobal architecture, in which one lobe contains the N-terminal and PAZ domainsExpand