Oliver Schaefer

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PURPOSE To evaluate traumatized bone marrow with a dual-energy (DE) computed tomographic (CT) virtual noncalcium technique. MATERIALS AND METHODS In this prospective institutional review board-approved study, 21 patients with an acute knee trauma underwent DE CT and magnetic resonance (MR) imaging. A software application was used to virtually subtract(More)
The aim of this study was to define the imaging characteristics of primary and recurrent gastrointestinal stromal tumors (GIST) in computed tomography with respect to the tumor size. Computed tomography was performed in 35 patients with histologically confirmed gastrointestinal stromal tumors and analyzed retrospectively by two experienced and independent(More)
The initial localization of metastases in the bone in patients with solid tumors has a relatively good prognosis in comparison with visceral metastasization. The early detection of bone marrow metastases allows for a rapid initiation of therapy and a subsequent reduction in the morbidity rate. Modern MRI is superior to the 30-year-old skeletal scintigraphy(More)
OBJECTIVES To investigate the effects, digital impression procedures can have on the three-dimensional fit of ceramic partial crowns in vitro. METHODS An acrylic model of a mandibular first molar was prepared to receive a partial coverage all-ceramic crown (mesio-occlusal-distal inlay preparation with reduction of all cusps and rounded shoulder finish(More)
AIM To evaluate the diagnostic value of whole-body magnetic resonance imaging (MRI) and skeletal scintigraphy in the detection of skeletal metastases in patients with solid tumors. MATERIALS AND METHODS One hundred and twenty-nine tumor patients were examined with whole-body MRI using coronal TIRM sequences for the different anatomical regions. Skeletal(More)
The N-terminally truncated form of the prion protein, PrP 27-30, and the corresponding recombinant protein, rPrP, were solubilized in 0.2% SDS, and the transitions induced by changing the conditions from 0.2% SDS to physiological conditions, i.e. removing SDS, were characterized with respect to solubility, resistance to proteolysis, secondary structure and(More)
The conversion of the alpha-helical, protease sensitive and noninfectious form of the prion protein (PrP(C)) into an insoluble, protease resistant, predominantly beta-sheeted and infectious form (PrP(Sc)) is the fundamental event in prion formation. In the present work, two soluble and stable intermediate structural states are newly identified for(More)
BACKGROUND Radiofrequency heat ablation (RFA) is an advanced minimal-invasive technique for the treatment of primary and secondary malignancies in several organs. This article presents the successful percutaneous computed tomography (CT)-guided radiofrequency heat ablation of a peripheral bronchiogenic carcinoma and four lung metastases in three patients.(More)
Vergleich des diagnostischen Stellenwerts der Ganzkörper-MRT (GK-MRT) als neues und schnelles Untersuchungsverfahren vs. Skelettszintigraphie (SKZ) bei der Erkennung ossärer Metastasen solider Tumoren. Bei 129 Patienten mit soliden Malignomen wurde eine GK-MRT im intraindividuellen Vergleich mit der SKZ durchgeführt. Zum Einsatz kamen der innovative(More)