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PURPOSE There is little known about how brain white matter structures differ in their response to radiation, which may have implications for radiation-induced neurocognitive impairment. We used diffusion tensor imaging (DTI) to examine regional variation in white matter changes following chemoradiotherapy. METHODS Fourteen patients receiving two or three(More)
Inference regarding the inclusion or exclusion of random effects in linear mixed models is challenging because the variance components are located on the boundary of their parameter space under the usual null hypothesis. As a result, the asymptotic null distribution of the Wald, score, and likelihood ratio tests will not have the typical χ(2) distribution.(More)
BACKGROUND Survival of patients with brain metastasis particularly from historically more radio-resistant malignancies remains dismal. A phase I study of concurrent bortezomib and whole brain radiotherapy was conducted to determine the tolerance and safety of this approach in patients with previously untreated brain metastasis. METHODS A phase I dose(More)
In this paper, we propose a method for obtaining a textured billboards representation of a static scene, given a sequence of calibrated video images. Each billboard is a textured and partially transparent plane into which the input images are mapped using perspective projection. Binning using Hough transform is used to find the position of the billboards,(More)
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