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RDC8 has been recently cloned and characterized as an adenosine A2 receptor. This receptor is expressed exclusively by medium-sized neurons of the striatum as demonstrated by in situ hybridization. We have now studied the relationship of this receptor with three major components of the rat caudate-putamen: enkephalin, substance P, and choline(More)
Accompanying the rise of mobile and pervasive computing, applications now need to adapt to their surrounding environments and provide users with information in the environment in an easy and natural manner. In this paper we describe a user interface that integrates multimodal input on a handheld device with external gestures performed with real world(More)
This paper reports on extensions to a decision-theoretic location-aware shopping guide and on the results of user studies that have accompanied its development. On the basis of the results of an earlier user study in a mock-up of a shopping mall, we implemented an improved version of the shopping guide. A new user study with the improved system in a real(More)
Current recommendations for mechanical ventilation in the acute respiratory distress syndrome (ARDS) include the use of small tidal volumes (VT), even at the cost of respiratory acidosis. We evaluated the effects of this permissive hypercapnia on pulmonary gas exchange with the multiple inert gas elimination technique (MIGET) in eight patients with ARDS.(More)
Eukaryotic tRNAs are transcribed as precursors. A 5'-end leader and 3'-end trailer are endonucleolytically removed by RNase P and 3'-tRNase before 3'-end CCA addition, aminoacylation, nuclear export and translation. 3'-End -CC can be a 3'-tRNase anti-determinant with the ability to prevent mature tRNA from recycling through 3'-tRNase. Twenty-two tRNAs(More)
A small surgical lesion of the parietal cortex induces an increase in the expression of several messenger RNAs varying from 172 to 980% in the entire homolateral cerebral cortex, as detected by quantitative in situ hybridization histochemistry. The messenger RNAs encoding the immediate early genes of the leucine zipper family (c-fos, c-jun, jun-B), the Zinc(More)
Smart labels enable novel item-centric ways of communication along a product’s lifecycle. With respect to the open nature of a scenario ranging from manufacturer to consumer, the expectations to such "smart items" are diverse. In this article, we discuss the perspective of potential users and system architects on selected aspects of so-called(More)