Olga Iljinskaya

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Under conditions of nitrogen limitation, the general transcription factor TnrA in Bacillus subtilis activates the expression of genes involved in assimilation of various nitrogen sources. Previously, TnrA activity has been shown to be controlled by protein-protein interaction with glutamine synthetase, the key enzyme of ammonia assimilation. Furthermore,(More)
Alterations in expression of surface adhesion molecules on resident vascular and blood-derived cells play a fundamental role in the pathogenesis of cardiovascular disease. Smooth muscle cells (SMCs) have been shown to express T-cadherin (T-cad), an unusual GPI-anchored member of the cadherin family of adhesion molecules. Particular relevance for T-cad in(More)
Phenotypic modulation, migration and proliferation of vascular smooth muscle cells (SMCs) are major events in restenosis after percutaneous transluminal angioplasty. Surface cell adhesion molecules, essential to morphogenesis and maintenance of adult tissue architecture, are likely to be involved, but little is known about cell adhesion molecules expressed(More)
Nitrogen is a macroelement for all living cells, from bacteria to animals. Although ammonia ions (NH3/NH 4 + ) are toxic to animals, they are the most preferable nitrogen source for the majority of bacteria and are assimilated by glutamine synthetase (GS) in the so-called GOGAT cycle. A lack of nitrogen for a cell triggers cascade regulatory processes and(More)
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