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Quantitative analysis of sleep EEG data can provide valuable additional information in sleep research. However, analysis of data contaminated by artifacts can lead to spurious results. Thus, the first step in realizing an automatic sleep analysis system is the implementation of a reliable and valid artifact processing strategy. This strategy should include:(More)
This study is aimed at verifying the functional independence of two frequency bands within the alpha range. It is based on experiments that examined the role of these two hands with regard to the amount of local electrogenesis (amplitude) and the cooperation of brain areas (coherence) in mental tasks concerning: (1) visual perception and imagery; (2)(More)
This pilot study examines the possibility to detect activities of SMA by means of EEG coherence analysis in a female professional violoncellist. The proband was asked, for 5 min each, to listen to a piece of music (she knew by heart), to imagine playing this piece and to imagine playing scales. The experiment was repeated after 5 days. Consistent(More)
This article deals with the estimation of event-related coherence (ERCoh) and its application to the planning and execution of self-paced index finger movement. ERCoh estimation complements the event-related desynchronization (ERD) measurements of rhythms within the alpha band. ERCoh yields information of the functional relationships between different brain(More)
Pain perception in the brain can be analyzed by neuroimaging (PET, fMRI) and electrophysiological parameter mapping (EEG, ERP/MEG, MEF). These studies have generally been focused on the localization of cerebral activation. Whether pain can be conceptualized as localized function or best be understood by distributed function is important to the theory of(More)
Drug-induced cardiac arrhythmia is acknowledged as a serious obstacle in successful development of new drugs. Several methods for in silico prediction of acquired long QT syndrome (LQTS) caused by the pharmacological blockade of human hERG K+ channels are discussed in literature. We propose to use the computer program PASS, which estimates the probabilities(More)
This exploratory study deals with EEG changes in 3 professional interpreters while mentally interpreting from their mother language into foreign languages and vice versa. EEGs were recorded while interpreting and compared with the periods at rest between these periods of interpreting. Significant (P < 0.05) changes of coherence between all pairs of(More)
Balanced modulation of several targets is one of the current strategies for the treatment of multi-factorial diseases. Based on the knowledge of inflammation mechanisms, it was inferred that the balanced inhibition of cyclooxygenase-1/cyclooxygenase-2/lipoxygenase might be a promising approach for treatment of such a multifactorial disease state as(More)
Artefact processing is an important issue in automated analysis of the sleep EEG. Nine artefact types were identified and their frequency of occurrence was analysed in 15 all-night sleep recordings from eight European sleep laboratories. Three artefact detection methods were evaluated with the area-under-ROC-curve (AUC), eight artefact minimisation methods(More)
Up until recently, neurology was dominated by localisatory thinking. Language and other so-called "centers" were considered to be centers of command controlling the respective functions. Today, there is general agreement that, instead, for every brain function numerous brain regions must act together. For the exploration of these manifold topographic(More)