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  • Olga D. Chuquimia, Dagbjort H. Petursdottir, M Jubayer Rahman, Katharina Hartl, Mahavir Singh, Carmen Fernández
  • Biology, Medicine
  • PloS one
  • 2012 (First Published: 29 February 2012)
  • Macrophages and dendritic cells have been recognized as key players in the defense against mycobacterial infection. However, more recently, other cells in the lungs such as alveolar epithelial cellsContinue Reading
    The respiratory epithelium is a physical and functional barrier actively involved in the clearance of environmental agents. The alveolar compartment is lined with membranous pneumocytes, known asContinue Reading
  • Chaniya Leepiyasakulchai, Chato Taher, +4 authors Markus Sköld
  • Biology, Medicine
  • PloS one
  • 2013 (First Published: 8 July 2013)
  • Non-hematopoietic cells, including lung epithelial cells, influence host immune responses. By co-culturing primary alveolar epithelial cells and monocytes from naïve donor mice, we show that alveolarContinue Reading
  • John Arko-Mensah, M Jubayer Rahman, +4 authors Carmen Adams Fernández
  • Biology, Medicine
  • Vaccine
  • 2009 (First Published: 1 December 2009)
  • In this study, we have compared the immunological responses associated with early pulmonary mycobacterial infection in two mouse strains, BALB/c and C57BL/6 known to exhibit distinct differences inContinue Reading
  • M Jubayer Rahman, Olga D. Chuquimia, Dagbjort H. Petursdottir, Natalia Periolo, Mahavir Singh, Carmen Fernández
  • Biology, Medicine
  • Infection and immunity
  • 2011 (First Published: 1 November 2011)
  • In the present study, we addressed the question of whether Toll-like receptor 2 (TLR2)-mediated innate immunity can contribute to the development of acquired immune responses. We immunized TLR2(-/-)Continue Reading
  • Dagbjort H. Petursdottir, Olga D. Chuquimia, Raphaela Freidl, Carmen Fernández
  • Biology, Medicine
  • PloS one
  • 2014 (First Published: 4 August 2014)
  • Tissue-resident macrophages are heterogeneous with tissue-specific and niche-specific functions. Thus, simplified models of macrophage activation do not explain the extent of heterogeneity seen inContinue Reading
  • Anette Schulz, Olga D. Chuquimia, +6 authors Keira Melican
  • Medicine, Chemistry
  • Pathogens and disease
  • 2018 (First Published: 1 November 2018)
  • Bacterial infection of the kidney leads to a rapid cascade of host protective responses, many of which are still poorly understood. We have previously shown that following kidney infection withContinue Reading