Olga Alekhina

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The chemokine receptor CXCR4 and its chemokine ligand CXCL12 mediate directed cell migration during organogenesis, immune responses, and metastatic disease. However, the mechanisms governing CXCL12/CXCR4-dependent chemotaxis remain poorly understood. Here, we show that the β-arrestin1·signal-transducing adaptor molecule 1 (STAM1) complex, initially(More)
AIM To ascertain the role of typical reactions of the immune system in early prognostication of congestive cardiac failure (CCF) in patients with primary transmural anterior myocardial infarction (MI) in the postinfarction period. MATERIAL AND METHODS Typical immune reactions were studied for a year after the disease onset. A total of 228 males aged 40-60(More)
Relationships between the quality of life (QL), psychological status and severity of cardiovascular impairment were studied in 96 males after anterior large-focal myocardial infarction. A positive moderately strong correlation was found between GL and left ventricular ejection fraction. Alexitimia affects the response of the patients to basic limitations(More)
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