- Full text PDF available (1)
- This year (6)
- Last 5 years (15)
- Last 10 years (26)
Journals and Conferences
CIDNP techniques were applied to the investigation of the elementary mechanism of photoinduced interaction between anti-arrhythmic drug lappaconitine and amino acids tyrosine and tryptophan. It has… (More)
(+)-Usninic acid was brominated at the acetyl group located on the aromatic ring. Aurones were synthesized based on the intramolecular cyclization of monobrominated (+)-usninic acid.
Usnic acid (UA) is a commercially available lichen metabolite. Its biological activity is diverse, and it is of interest for pharmacopoeia. The second part of the review is dedicated to the… (More)
Enamine-derivatives of both enantiomers of usnic acid and the corresponding compounds with a quaternized N atom were synthesized. Compounds 3 and 4 exhibited moderate cytotoxic activity. All… (More)
Tyrosyl-DNA phosphodiesterase 1 (Tdp1) is a repair enzyme for stalled DNA-topoisomerase 1 (Top 1) cleavage complexes and other 3'-end DNA lesions. Tdp1 is a promising target for anticancer therapy,… (More)
Sulfides containing the pharmacophore (+)-usninic acid and its methyl ether were synthesized from monobrominated precursors.
INTRODUCTION Usnic acid (UA) is a lichen-derived secondary metabolite with a unique dibenzofuran skeleton and is commonly found in lichenized fungi of the genera Usnea and Cladonia. Usnic acid has… (More)
The reaction of (+)-usninic acid and its pyrazole derivative with sodium borohydride was studied. The reduction occurred stereoselectively at the endocyclic carbonyl group. Novel (+)-usninic acid… (More)
New usnic acid (UA) derivatives were investigated in vitro to elucidate their potential inhibitory activities on the growth of Mycobacterium smegmatis and Mycobacterium tuberculosis. Seven pairs of… (More)
Usnic acid, a lichen secondary metabolite produced by a whole number of lichens, has attracted the interest of researchers owing to its broad range of biological activity, including antiviral,… (More)