Olga A Prokhorenko

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OBJECTIVE To determine if modafinil can improve fatigue in patients with post-polio syndrome. METHODS We used a randomized, placebo-controlled crossover trial. Intervention with modafinil (400 mg/day) and placebo occurred over 6-week periods. Primary endpoint (fatigue) was assessed using the Fatigue Severity Scale as the main outcome measure. Other(More)
Traumatic brain injuries (TBI) sustained in combat frequently co-occur with significant bodily injuries. Intuitively, more extensive bodily injuries might be associated with increased symptom reporting. In 2012, however, French et al. demonstrated an inverse relation between bodily injury severity and symptom reporting. This study expands on that work by(More)
BACKGROUND Headaches can be triggered by a variety of factors. Military service members have a high prevalence of headache but the factors triggering headaches in military troops have not been identified. OBJECTIVE The objective of this study is to determine headache triggers in soldiers and military beneficiaries seeking specialty care for headaches. (More)
OBJECTIVE To study the role of mild brain injury in intractable epilepsy. METHODS The medical charts of 86 patients who underwent surgery for intractable epilepsy were reviewed in regard to the history of mild brain injury, pathology and surgical outcome. RESULTS Nine of 86 patients had a previous history of mild brain injury (10.4%) compared to 2.5% of(More)
OBJECTIVE To explore the taxonomy of combat-related mild traumatic brain injury (mTBI) based on symptom patterns. PARTICIPANTS Up to 1341 military personnel who experienced a combat-related mTBI within 2 years of evaluation. MEASURES Neurobehavioral Symptom Inventory and PTSD Checklist-Civilian Version (PCL-C). RESULTS Cluster analysis revealed the(More)
We hypothesized that the corticospinal system undergoes functional changes in long-term polio survivors. Central motor conduction times (CMCTs) to the four limbs were measured in 24 polio survivors using transcranial magnetic stimulation (TMS). Resting motor thresholds and CMCTs were normal. In 17 subjects whose legs were affected by polio and 13 healthy(More)
OBJECTIVE To examine the applicability and validity of traditional fatigue questionnaires in postpoliomyelitis syndrome (PPS) patients with disabling fatigue. DESIGN Cross-sectional study. PPS and disabling fatigue were ascertained according to published criteria. Descriptiveness was determined using the McNemar test, and interscale z-score agreement was(More)
Functional inhibition of the drug liver metabolism seems to start at early subclinical stages of cholecystitis. Antipyrine++ level in the initial saliva sample drops significantly and continues to change with growing structural impairment of the biliary system in progression of chronic noncalculous cholecystitis into calculous one.
Evidence suggests that sensory loss may occur in a proportion of patients affected by poliomyelitis. We hypothesize that sensory problems may be a lasting sequela in some polio survivors. Sensory pathways in polio survivors were evaluated clinically and electrophysiologically using sensory evoked potentials (SEPs). Patients with sensory deficits or abnormal(More)
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