Ole Simon

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The aim of the present study was to assess variability in the evaluation of human sperm concentration, motility and vitality. Technicians and biologists from 10 teams involved in multicentre studies on semen quality attended the same laboratory, each team using its own methods and equipment to analyse the same semen samples. Inter-individual variability was(More)
Thirty-two hours (night-day-night) of polygraphic recordings were performed on 14 patients with a diagnosis of narcolepsy-cataplexy. Half of the patients stayed in bed during the day, whereas the other half were seated at a table. Patients were free to nap whenever they wanted to. Patients under continuous bedrest slept 2-3 times more during the day than(More)
APOL1, a secreted high-density lipoprotein, is expressed in different human tissues. Genetic variants of APOL1 are described to be associated with the development of end stage renal diseases in African Americans. In human kidney, APOL1 is mainly expressed in podocytes that are responsible for proper blood filtration. Since mice do not express ApoL1, the(More)
Spinal tape syndrome requires rapid diagnosis and adapted treatment. A relatively small diameter needle inserted parallel to the dura mata fibers is the best preventive measure. The ventral supine position for a few hours followed by a short walk is sufficient. Caffeine may also be prescribed and has been shown to be as effective orally or intravenously.(More)
Seven patients with narcolepsy-cataplexy were continuously monitored during the day using polygraphy and videotape recording. The patients were free to do whatever they wanted while confined to a sitting-at-a-table situation. Daytime activity was evaluated by distinguishing between two polygraphically defined states, namely active wakefulness and quiet(More)
Six manic patients, drug-free for at least 10 days, were treated with high doses (up to 3,000 mg/day, corresponding serum levels up to 1,600 ng/ml) of d-propranolol or dl-propranolol in a double-blind, placebo-controlled study. The EEG's of these patients were studied over a maximum period of 21 days. All 82 EEG's were normal, they showed neither epileptic(More)
Polygraphic examinations were made during the day on 6 normal subjects. Simultaneous evaluation of EEG, EOG and EMG was carried out over 30 sec epochs. The data thus obtained were correlated with the various types of behaviour and activities during the day and then interpreted. Six conditions could be defined corresponding to different waking stages. The(More)
Open- and closed-eyed EEG records were made in frontal, temporal and occipital regions, in order to examine the time relationships between various of their characteristics, in connection with the appearance of subclinical seizure patterns. 1. In the range of alpha frequency, both with open and closed eyes, the standard deviation of frequency over all brain(More)
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