Olarewaju M. Oluba

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The effect of water contaminated with phenol, benzene and lead on rats cellular system was investigated. Selected enzyme activity of the kidney and colon of rats was carried out. Standard enzyme assays were also conducted for selected liver enzymes such as alkaline and acid phosphatases, alanine and aspartate transaminases, and gamma glutamyl(More)
In this study, attempt is made to establish changes in serum and liver lipoprotein cholesterols accompanying Plasmodium berghei malarial infection in mice treated with aqueous extract of Ganoderma lucidum at 100, 250, and 500 mg/kg body weight in comparison with 15 mg/kg chloroquine (CQ). Significant increases in all the lipoprotein fractions were observed(More)
This study was aimed at investigating the in vivo antimalarial activity (using some biochemical indices) of crude aqueous extracts of the fruiting bodies of Ganoderma lucidum, a mushroom with well-established medicinal properties. A rodent malaria parasite, Plasmodium berghei (1 × 107), was inoculated intraperitoneally into Swiss albino mice. The test(More)
A cholesterol-enriched diet has been shown to adversely affect lipoprotein profiles and increase cardiovascular disease risk. Dietary cholesterol plays an important role in modulating inflammatory responses involved in atherosclerosis. In the present study, the effect of Oryctes rhinoceros larva oil (ORO), an unsaturated fatty acid-rich animal fat, on serum(More)
Hematological and antioxidant effects of the aqueous extract of fruiting bodies of Ganoderma lucidum were evaluated in Plasmodium berghei-infected mice. Extract was administered at doses of 100, 250, and 500 mg/kg body weight by an intragastric tube once daily for 14 d starting from the fourth day after parasite inoculation. At the end of treatment period,(More)
The effect of soy protein on serum lipid profile and some lipid metabolizing enzymes in rats fed with cholesterol diets was examined in this study. Rats were subjected to feeding trial over a period of six weeks on formulated diets containing: 20% soy protein with 0% cholesterol (group A); 20% soy protein with 5% cholesterol (group B), 20% soy protein with(More)
From our previous study extract of the fruit bodies of Ganoderma lucidum possessed promising curative potential against Plasmodium berghei in mice. Thus, we hypothesized that infection with chloroquine-sensitive Plasmodium berghei together with crude chloroform extract (CCE) of G. lucidum, at 250 mg/kg body weight would enhance various aspects of(More)
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