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In a prospective study of 154 AIDS patients, 48 (31%) complained of pain on swallowing both liquids and solids and 32 (21%) of these also had dysphagia. While candidiasis was the most common cause of symptoms (26 patients), discrete ulceration of the oesophagus occurred in 12 instances in 10 patients (four cytomegalovirus, four herpes simplex virus, three(More)
ISSUES Cell Preparation Methods Standardized fixation and optimal staining Sampling of cervix, sampling error, homogenization of sample, subsampling Assessment of liquid-based preparations: efficacy and economic impact Training and transitional procedures before full implementation of new technologies Criteria for Sample Adequacy Clinician responsibility(More)
This study was designed to determine whether immunohistochemical stains for tumour-associated markers may be useful in the detection and differential diagnosis of premalignant and malignant lesions of the cervix. The expression of four markers detected by monoclonal antibodies, human milk fat globule 1 and 2 (HMFG-1 and 2), Ca1 and anti-carcinoembryonic(More)
OBJECTIVE To collect information from children and young people about their knowledge of and attitudes towards cancer and their understanding of health and health related behaviours to inform future health promotion work. DESIGN Questionnaire survey of 15-16 year olds, and interviews with play materials with 9-10 year old children. SETTING Six inner(More)
The introduction of cationic polyelectrolytes as cellular adherents has significantly advanced the preparation of cervical scrape specimens for automated cell scanning and has also provided an efficient technique for the preparation of cell monolayers of other cytologic specimens, e.g., breast cyst fluids, urines and serous effusions, for diagnostic(More)
A retrospective analysis was carried out on a consecutive series of 181 percutaneous fine needle aspiration biopsies of discrete pulmonary lesions, in which the outcome was established in 95%. In primary bronchial carcinoma the technique had a sensitivity of 86%. There was no relationship between the size, location, or radiological appearance of the lesion(More)
The Papnet was given a mini-challenge of 200 cervical smears loaded to 50% with varying degrees of abnormality as interpreted by the originating laboratory. The range of abnormality extended from 'atypia' to invasive cancer and a few 'glandular' lesions were included as were a few smears which had been reported as 'inadequate'. Three cytologists (two(More)
51 patients infected with the human immunodeficiency virus (HIV) and with suspected Pneumocystis carinii pneumonia underwent sputum induction. Sputum specimens from 18 patients were positive for P carinii and patients were treated appropriately 25 of the 33 patients with negative specimens underwent bronchoscopy and bronchoalveolar lavage within 4 days of(More)