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Suppression of inducible nitric oxide synthase expression in RAW 264. 7 macrophages by two beta-carboline alkaloids extracted from Melia azedarach.
We investigated the mechanism of suppression of inducible nitric oxide synthase (iNOS) by two beta-carboline alkaloids isolated from Melia azedarach, 4,8-dimethoxy-1-vinyl-beta-carboline (compound 1,Expand
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Antioxidative iridoid glycosides and phenolic compounds from Veronica peregrina
Eight iridoid glycosides and four phenolic compounds were isolated from the EtOAc soluble fraction of Veronica peregrina MeOH extract as the radical scavengers for antioxidant activity. The compoundsExpand
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Antitumor activity of some phenolic components in plants
The activity-guided fractionation of some medicinal plants led to yield five kinds of natural stilbene compounds namely 3,5-dihydroxy-4′-methoxystillbene(I), rhapontigenin(II), resveratrol (III),Expand
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Four new cytotoxic germacranolides from Carpesium divaricatum.
In a bioassay-guided search for cytotoxic compounds from higher plants of South Korea, four new sesquiterpenes of the germacranolide type, named cardivins A (1), B (2), C (3), and D (4), have beenExpand
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Two new lignans fromLindera obtusiloba blume
Two new furanolignans (3, 5), together with three known lignans (1, 2, 4), were isolated from the stem ofLindera obtusiloba (Lauraceae). The structures of the compounds were determined as actifolinExpand
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Inducible nitric oxide synthase inhibitors fromMelia azedarach var.Japonica
  • H. Kwon, B. Lee, +6 authors K. Lee
  • Chemistry, Medicine
  • Archives of pharmacal research
  • 1 August 1999
In bioassay-guided search for inducible nitric oxide synthase (iNOS) inhibitory compounds from higher plants of South Korea, two β-carboline alkaloids, 4-methoxy-1-vinyl-β-carboline (1) andExpand
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Evaluation of oriental medicinal herbs for estrogenic and antiproliferative activities
Herb extracts commercially used in Asia were screened for their estrogenic activity with a recombinant yeast system with both a human estrogen receptor (ER) expression plasmid and a reporter plasmid.Expand
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Cytotoxic phenolic compounds from Chionanthus retusus
Cytotoxicity-guided fractionation and purification of MeOH extract from Chionanthus retusus Lindl. et Paxton resulted in the isolation of compounds. Fourteen phenolic compounds were isolated from theExpand
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Cytotoxic constituents ofPilea mongolica
Bioassay-guided fractionation of the aerial parts ofPilea mongolica (Urticaceae) afforded two cytotoxic triterpenoids, epi-oleanolic acid (I) and oxo-oleanolic acid (II). The structures of theExpand
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Antitumor and immunomodulating activities of the polysaccharide fractions fromArtemisia selengensis andArtemisia iwayomogi
Effects of the polysaccharide fractions purified fromArtemisia selengensis andArtemisia iwayomogi on the immune system was studied. The polysaccharide fractions, respectively called ASP1 and AIP1,Expand
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