Oi Ka Catherine Chan

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OBJECTIVE To assess the effect of increasing body mass index (BMI) on pregnancy outcome in a population of Chinese women. DESIGN A retrospective study. SETTING A university teaching hospital. POPULATION Women delivering singleton babies between 1995 and 2005 who sought antenatal care before 20 weeks of gestation. METHODS A total of 29,303 women were(More)
OBJECTIVE To assess pre-induction sonographic, digital examination and biochemical changes in the cervix to predict induction outcome. METHODS Transvaginal and abdominal scans were performed in 460 women at 37-41 weeks of gestation to determine cervical length (CL), posterior cervical angle (PCA) and foetal occipital position. The Bishop Score (BS) and(More)
BACKGROUND Hepatitis B virus (HBV) infection remains a global public health problem and it is an important cause of acute, chronic and fulminant hepatitis, liver cirrhosis and hepatocellular carcinoma. The prevalence of HBV infection in Hong Kong over the past decade remained unchanged at 10%, despite the implementation of universal neonatal and(More)
BACKGROUND Nausea and vomiting in pregnancy (NVP) is the most common pregnancy complication affecting women during the first trimester of pregnancy. The cause of NVP remains unknown and factors associated with the occurrence of NVP are contradictory. There is currently little information on its effects of NVP in general and specifically in the Chinese(More)
Hepatitis B infection is a major global health problem. Vertical transmission is the commonest route of spreading hepatitis B virus (HBV) in many endemic areas. In order to control such transmission in Hong Kong, neonatal immunization programme was implemented for more than two decades. A declining prevalence of HBV infection was expected. However, the(More)
OBJECTIVE To compare seroprevalence (serum IgG titre) with self-reported history of varicella zoster virus (VZV) infection among pregnant women in Hong Kong. METHODS Pregnant women undergoing first trimester Down screening over a 3-months period were recruited for the study. RESULTS Positive immunity was found in 477 (95.4%) of the 500 recruited women,(More)
OBJECTIVE To determine the prevalence of a history of hepatitis B vaccination among pregnant Chinese women in Hong Kong, and to identify factors associated with vaccine uptake at their own expense. METHODS A prospective, cross-sectional survey was conducted in a university obstetric unit in Hong Kong. Pregnant Chinese women who attended the prenatal(More)
BACKGROUND Spontaneous preterm birth (SPB, before 37 gestational weeks) is a major cause of perinatal mortality and morbidity, but its pathogenesis remains unclear. Studies on SPB have been hampered by the limited availability of markers for SPB in predelivery clinical samples that can be easily compared with gestational age-matched normal controls. We(More)
OBJECTIVE To assess how pregnant women choose between a non-invasive DNA test (NIDT) and an invasive prenatal test (IPD) based on the accuracy of the test. MATERIALS AND METHODS Pregnant women who attended for first-trimester combined screening assessment of risk of Down syndrome were invited to participate in an interviewer-administered survey. Women(More)
OBJECTIVE To assess Chinese women's preference for the choice of a prenatal diagnosis test, karyotyping or rapid aneuploidy, and its relationship to maternal psychological state. STUDY DESIGN Three hundred consenting women completed a self administered structured questionnaire which documented their psychological state and their preferred choice of(More)