Oguzhan Alagöz

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L donors are a significant and increasing source of livers for transplantation, mainly because of the insufficient supply of cadaveric organs. We consider the problem of optimally timing a living-donor liver transplant to maximize the patient’s total reward, such as quality-adjusted life expectancy. We formulate a Markov decision process (MDP) model in(More)
The only available therapy for patients with end-stage liver disease is organ transplantation. In the United States, patients with end-stage liver disease are placed on a waiting list and offered livers based on location and waiting time, as well as current and past health. Although there is a shortage of cadaveric livers, 45% of all cadaveric liver offers(More)
Breast cancer is the most common non-skin cancer and the second leading cause of cancer-death in US women. Although mammography is the most effective modality for breast cancer diagnosis, it has several potential risks, including high false positive rates, which are not very rare. Therefore, the balance of benefits and risks, which depend on personal(More)
We consider the problem of designing an efficient liver allocation system for allocating donated organs to patients waiting for transplantation, the only viable treatment for end-stage liver disease. Given the scarcity of available organs relative to the number of patients waiting for transplantation, we model the system as a multiclass fluid model of(More)
Breast cancer is the most common non-skin cancer affecting women in the United States, where every year more than 20 million mammograms are performed. Breast biopsy is commonly performed on the suspicious findings on mammograms to confirm the presence of cancer. Currently, 700,000 biopsies are performed annually in the U.S.; 55%-85% of these biopsies(More)
T only therapy for a patient with end-stage liver disease (ESLD) is liver transplantation, which is performed by using either a cadaveric liver from a deceased donor or a portion of a living-donor’s liver. This study addresses the following decision problem for an ESLD patient with an available living donor. Should she have a transplantation now or wait? If(More)
While chemotherapy is an effective method for treating cancers such as colorectal cancer, its effectiveness may be dampened by the drug resistance and it may have significant side effects due to the destruction of normal cells during the treatment. As a result, there is a need for research on choosing an optimal chemotherapy treatment plan that minimizes(More)
Exceptional opportunities exist for researchers and practitioners to invest in conducting innovative and transformative research in data mining and health informatics. This IEEE Intelligent Systems "Trends and Controversies" (T&C) department hopes to raise awareness and highlight recent research to move toward such goals. The introduction, "Healthcare(More)
In this paper, we apply game theory to model strategies of secrecy and deception in a multiple-period attacker–defender resource-allocation and signaling game with incomplete information. At each period, we allow one of the three possible types of defender signals—truthful disclosure, secrecy, and deception. We also allow two types of information(More)