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The only available therapy for patients with end-stage liver disease is organ transplantation. In the United States, patients with end-stage liver disease are placed on a waiting list and offered livers based on location and waiting time, as well as current and past health. Although there is a shortage of cadaveric livers, 45% of all cadaveric liver offers(More)
T he only therapy for a patient with end-stage liver disease (ESLD) is liver transplantation, which is performed by using either a cadaveric liver from a deceased donor or a portion of a living-donor's liver. This study addresses the following decision problem for an ESLD patient with an available living donor. Should she have a transplantation now or wait?(More)
While chemotherapy is an effective method for treating cancers such as colorectal cancer, its effectiveness may be dampened by the drug resistance and it may have significant side effects due to the destruction of normal cells during the treatment. As a result, there is a need for research on choosing an optimal chemotherapy treatment plan that minimizes(More)
Exceptional opportunities exist for researchers and practitioners to invest in conducting innovative and transformative research in data mining and health informatics. This IEEE Intelligent Systems "Trends and Controversies" (T&C) department hopes to raise awareness and highlight recent research to move toward such goals. The introduction, "Healthcare(More)
Keywords: Game theory Signaling game Secrecy and deception Truthful disclosure Dynamic programming Multi-period game a b s t r a c t In this paper, we apply game theory to model strategies of secrecy and deception in a multiple-period attacker–defender resource-allocation and signaling game with incomplete information. At each period, we allow one of the(More)
Breast cancer is the most common non-skin cancer affecting women in the United States, where every year more than 20 million mammograms are performed. Breast biopsy is commonly performed on the suspicious findings on mammograms to confirm the presence of cancer. Currently, 700,000 biopsies are performed annually in the U.S.; 55%-85% of these biopsies(More)
In the United States, patients with end-stage liver disease must join a waiting list to be eligible for cadaveric liver trans-plantation. Due to privacy concerns, the details of the composition of this waiting list are not publicly available. This paper considers the benefits associated with creating a more transparent waiting list. We study these benefits(More)