Odile Noizet

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INTRODUCTION Two generic paediatric mortality scoring systems have been validated in the paediatric intensive care unit (PICU). Paediatric RISk of Mortality (PRISM) requires an observation period of 24 hours, and PRISM III measures severity at two time points (at 12 hours and 24 hours) after admission, which represents a limitation for clinical trials that(More)
The most common cause of subdural hematomas (SDH) in infants is shaken-baby syndrome (SBS). The pathogenesis and natural history of infantile SDH (ISDH) are poorly documented, because in SBS, the date of shaking is usually imprecise and the assault is often repeated. Victims of traffic accidents (TA) form a study group close to experimental conditions,(More)
OBJECTIVE Vasopressin (AVP) response has been reported to be inappropriately low in adult established septic shock. We studied admission AVP levels in children with meningococcal septic shock (MSS). PATIENTS AND METHODS All children with meningococcal infection admitted to our PICU between May 2001 and August 2002 were classified as MSS (persistent(More)
UNLABELLED Beneficial effect of continuous positive airway pressure (CPAP) during non invasive ventilation (NIV) has been reported in infants with respiratory syncytial virus (RSV) infection, but no study has analyzed the predictors of its failure. OBJECTIVE To evaluate the feasibility of NIV and to determine NIV failure criteria. POPULATION AND METHODS(More)
Paediatric intensive care and haematological units are ideal sites for the development of nosocomial infections. These infections remain a significant source of mortality and morbidity and increase length of stay and costs. Selective digestive decontamination (SDD) includes topical antibiotics during the entire intensive care unit (ICU) stay, parenteral(More)
PURPOSE To document in patients with meningococcal purpura fulminans (PF), the effects of a combined supplementation with antithrombin (AT) and protein C (PC) plasma concentrates and to estimate the pharmacokinetics and dose requirements of each inhibitor. DESIGN Retrospective study of 15 patients. SETTING. One paediatric and one adult ICU in a university(More)
The process of weaning from mechanical ventilation (WMV) is the same in children as in adults. In the pediatric literature, weaning failure rate ranges from 1.4 to 34%. So far, no indices of weaning success have been demonstrated to be sufficiently accurate. The criteria for assessing readiness to wean, which must be screened daily, have neither been(More)
OBJECTIVE To report two children admitted to our emergency department with respiratory failure, one for status asthmaticus with pneumomediastinum and requiring mechanical ventilation and the other for high suspicion of foreign body aspiration. INTERVENTIONS Bronchoscopy revealed obstructive plugs and permitted their extraction and their identification as(More)
OBJECTIVES To assess the reproducibility of respiratory dead space measurements in ventilated children. DESIGN Prospective study. SETTING University pediatric intensive care unit. PATIENTS Thirty-two mechanically ventilated children (0.13-15.4 years) who were clinically stable. METHODS The single-breath CO(2) test (SBT-CO(2)) was recorded using the(More)
OBJECTIVE To evaluate feasibility of the guidelines of the Groupe Francophone de Réanimation et Urgence Pédiatriques (French-speaking group of paediatric intensive and emergency care; GFRUP) for limitation of treatments in the paediatric intensive care unit (PICU). DESIGN A 2-year prospective survey. SETTING A 12-bed PICU at the Hôpital Jeanne de(More)