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 Fungal infections are an important cause of morbidity and mortality in patients with acute leukemia (AL). Candidemia, once rare, is now a common nosocomial infection because of the intensity of chemotherapy, prolonged neutropenia, administration of broad-spectrum antibiotics and use of central venous catheters (CVC). We retrospectively identified patients(More)
The objective of the current study was to adapt and validate the Roland Morris disability questionnaire (RMDQ) to the Portuguese patients because there are no European Portuguese psychometric instruments to evaluate patients suffering from low back pain. After translation and back translation the Portuguese version of the RMDQ was tested in 112 patients(More)
The impact on occult leukemia of GM-CSF as a sensitizing agent has not been studied. We treated 41 adult patients with de novo acute myeloid leukemia, 25 of whom achieved complete remission and were given 1 to 3 post-remission courses, each course including GM-CSF begun 4 days prior to chemotherapy and given until day 3. After a median follow-up of 32(More)
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