Oana Covasala

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Calcitonin gene-related peptide (CGRP) is regarded as a key mediator in the generation of primary headaches. CGRP receptor antagonists reduce migraine pain in clinical trials and spinal trigeminal activity in animal experiments. The site of CGRP receptor inhibition causing these effects is debated. Activation and inhibition of CGRP receptors in the(More)
8 Calcitonin gene-related peptide (CGRP) is regarded as a key mediator in the 9 generation of primary headaches. CGRP receptor antagonists reduced migraine pain 10 in clinical trials and spinal trigeminal activity in animal experiments. The site of CGRP 11 receptor inhibition causing these effects is debated. Activation and inhibition of CGRP 12 receptors(More)
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