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OBJECTIVE To investigate the effect of continuous high-volume hemofiltration (HVHF) on extravascular lung water and respiratory mechanics in patients with acute respiratory distress syndrome (ARDS) and multiple organ dysfunction syndrome (MODS). METHODS Forty-one patients with ARDS and MODS were randomized into control group (20 patients) and HVHF(More)
Extracorporeal detoxication methods (hemofiltration, discrete exchange and filtration plasmapheresis) were added to intensive care complexes for 53 patients with pancreonecrosis. Peritonitis with multiple organ dysfunction was diagnosed in all patients. The severity of intoxication, central hemodynamic parameters, blood gaseous composition were evaluated in(More)
Introduction High-volume hemofiltration (HVHF) is technically possible in severe acute disease abdominal cavity patients complicated with multiple organ dysfunction syndrome (MODS). Continuous HVHF is expected to become a beneficial adjunct therapy for acute pancreatitis and peritonitis complicated with MODS. In this study, we aimed to explore the effects(More)
Effects of hemofiltration (HF) on central hemodynamics and oxygen transport are studied in 35 patients with surgical sepsis and multiple organ failure. HF is paralleled by development of hypovolemia and decrease of myocardial contractility, determining a decrease in cardiac output and oxygen transport. As a result, oxygen utilization by tissues decreases(More)
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