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Involvement of cortisol and metallothionein-like proteins in the physiological responses of tilapia (Oreochromis mossambicus) to sublethal cadmium stress
It is concluded that, in tilapia, cortisol, by initiating physiological responses and via possible synergism with other hormones like prolactin, enables the fish to counter-act the adverse effects of Cd.
Cell-membrane damage and element leaching in transplanted Parmelia sulcata lichen related to ambient SO2, temperature, and precipitation.
- A. Marques, M. Freitas, H. Wolterbeek, O. Steinebach, T. Verburg, J. D. de Goeij
- Chemistry, MedicineEnvironmental science & technology
- 11 March 2005
The present data suggest that the comparability of lichen vitality in large geographical areas may be limited and governed by the area's variability in temperature and precipitation rather than by variability in metal deposition rates.
Metallothionein biodegradation in rat hepatoma cells: a compartmental analysis aided 35S-radiotracer study.
Overall rates of disappearance of [35S]MT did not obey first-order kinetics, apparently due to the presence of chemically and/or spatially distinguishable MT (sub)pools, and MT behaviour may be best examined by combination of tracer experiments, simultaneous determination of MT levels in all (sub).
Studies on production of high specific activity 99Mo and 90Y by Szilard Chalmers reaction
Abstract Attempts have been made to use Szilard Chalmers reaction to prepare 99Mo and 90Y in high specific activity. Experiments were carried out using irradiation of freshly prepared oxinate…
The effects of pH and ionic strength on cytochrome c oxidase steady-state kinetics reveal a catalytic and a non-catalytic interaction domain for cytochrome c.
- K. Sinjorgo, O. Steinebach, H. Dekker, A. Muijsers
- Chemistry, MedicineBiochimica et biophysica acta
- 10 June 1986
A qualitative description of electrostatic interactions between the two cytochromes based on limited electrostatic interaction domains on the cytochrome c oxidase surface was found to be in good agreement with all data and supports the model of Speck et al.
Effects of zinc on rat hepatoma HTC cells and primary cultured rat hepatocytes.
The overall results indicate that synthesis of (protective) cellular compounds like MT or GSH, although rendering cells resistant to metals, may--at the same time--result in relatively strong accumulation of potentially toxic metals.
Role of cytosolic copper, metallothionein and glutathione in copper toxicity in rat hepatoma tissue culture cells.
The results presented support a model for copper metabolism in hepatoma tissue culture (HTC) cells, where Cu(I) is complexed by GSH immediately after entering the cell, and HTC cells rapidly loose their resistance to copper toxicity, as also reflected in loss of cell viability.
Effects of cadmium, copper and metallothionein synthesis inhibiting and stimulating compounds on zinc uptake and accumulation in rat hepatoma HTC cells.
The results indicate that cellular responses in rat hepatoma HTC cells with respect to the uptake and accumulation of 65Zn are fully comparable with literature data existing, and suggest the relatively easy Zn-complexing and ZN-release of MT.
Effects of copper on rat hepatoma HTC cells and primary cultured rat hepatocytes.
It is shown that hepatoma HTC cells are more capable of dealing with high accumulated Cu levels than the better established rat hepatocytes, and Metallothionein synthesis rendered both cell types well equipped to deal with increasing intracellular copper levels.
Radioactive Holmium Acetylacetonate Microspheres for Interstitial Microbrachytherapy: An In Vitro and In Vivo Stability Study
- W. Bult, H. de Leeuw, +7 authors J. Nijsen
- Chemistry, MedicinePharmaceutical Research
- 9 November 2011
HoAcAcMS are stable both in vitro and in vivo and are suitable for intratumoral radionuclide treatment of solid malignancies.